Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3939083 | 1.00 | KDM4E (0.53) | KDM4EHSD17B10MAPTL3MBTL1PARP1 | |
| SCHEMBL3939079 | 1.00 | KDM4E (0.53) | KDM4EHSD17B10MAPTL3MBTL1PARP1 | |
| SCHEMBL4883820 | 0.89 | KDM4E (0.61) | KDM4EHSD17B10MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL4883834 | 0.89 | KDM4E (0.61) | KDM4EHSD17B10MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL5550186 | 0.87 | KDM4E (0.51) | KDM4EHSD17B10MAPTL3MBTL1PARP1 | |
| SCHEMBL971939 | 0.87 | KDM4E (0.53) | KDM4EHSD17B10MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL971938 | 0.87 | KDM4E (0.53) | KDM4EHSD17B10MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL974414 | 0.86 | KDM4E (0.56) | KDM4EHSD17B10MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL974413 | 0.86 | KDM4E (0.56) | KDM4EHSD17B10MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL4875973 | 0.85 | KDM4E (0.55) | KDM4EHSD17B10MAPTL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786792-B1 | THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY | ASTELLAS PHARMA INC (JP) | 2009-04-08 | — | — | EP | disclosed |