Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL980366 | 0.88 | S1PR1 (0.47) | EPHX2EPHX1CA12CA1CA2 | |
| SCHEMBL979925 | 0.81 | EPHX2 (0.47) | EPHX2EPHX1CA12CA1CA2 | |
| SCHEMBL978582 | 0.81 | S1PR1 (0.45) | EPHX2EPHX1CA12CA1CA2 | |
| SCHEMBL979229 | 0.81 | S1PR1 (0.47) | EPHX2EPHX1CA12CA1CA2 | |
| SCHEMBL979549 | 0.80 | S1PR1 (0.39) | EPHX2EPHX1CA12CA1CA2 | |
| Iodide SCHEMBL980182 | 0.79 | EPHX2 (0.46) | EPHX2EPHX1CA12CA1CA2 | |
| SCHEMBL31267714 | 0.78 | SPHK1 (0.47) | SPHK1HPGDNPC1RAB9ATHRA | |
| Iodide SCHEMBL979814 | 0.78 | S1PR1 (0.46) | EPHX2EPHX1CA12CA1CA2 | |
| SCHEMBL980299 | 0.78 | EPHX2 (0.44) | EPHX2EPHX1CA12CA1CA2 | |
| Iodide SCHEMBL978539 | 0.76 | EPHX2 (0.43) | EPHX2EPHX1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009015485-A1 | CYCLIC INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK (CA) | 2009-02-05 | — | — | WO | disclosed |