Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL778862 | 0.99 | KCNH2 (0.62) | CHRNA7KCNH2 | |
| SCHEMBL779030 | 0.92 | CHRNA7 (0.70) | CHRNA7KCNH2 | |
| Hydrochloric Acid SCHEMBL779532 | 0.91 | KCNH2 (0.70) | CHRNA7KCNH2 | |
| SCHEMBL780359 | 0.91 | CHRNA7 (0.59) | CHRNA7KCNH2 | |
| SCHEMBL778287 | 0.91 | CHRNA7 (0.59) | CHRNA7KCNH2 | |
| Hydrochloric Acid SCHEMBL778661 | 0.90 | KCNH2 (0.60) | CHRNA7KCNH2 | |
| Hydrochloric Acid SCHEMBL780603 | 0.90 | KCNH2 (0.60) | CHRNA7KCNH2 | |
| SCHEMBL779728 | 0.90 | CHRNA7 (0.64) | CHRNA7KCNH2 | |
| Hydrochloric Acid SCHEMBL1775595 | 0.89 | KCNH2 (0.64) | CHRNA7KCNH2 | |
| SCHEMBL12210164 | 0.87 | CHRNA7 (0.52) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044038-B1 | NOVEL PIPERAZINES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF | CORNERSTONE THERAPEUTICS INC (US) | 2014-07-02 | — | — | EP | claimed |
| EP-2044038-A2 | NOVEL PIPERAZINES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF | Cornerstone Therapeutics Inc. (US) | 2009-04-08 | — | — | EP | claimed |
| WO-2007146066-A2 | NOVEL PIPERAZINES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF | CRITICAL THERAPEUTICS, INC. (US) | 2007-12-21 | — | — | WO | claimed |