Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 20/20 | 1.00 |
| ▸ | CCR3 | P51677 | 20/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3938647 | 1.00 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL3945874 | 1.00 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL4188358 | 1.00 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL4187960 | 1.00 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL18841185 | 1.00 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL3938653 | 1.00 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL3938852 | 0.85 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL5191532 | 0.84 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL5190328 | 0.84 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL5189859 | 0.84 | HRH1 (1.00) | HRH1CCR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517989-B2 | Piperidine derivatives useful as modulators of chemokine receptor activity | ASTRAZENECA AB (SE) | 2009-04-14 | — | — | US | disclosed |