Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL505669 | 0.93 | CA14 (0.46) | CA14HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL12924141 | 0.93 | CA14 (0.46) | CA14HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL12924143 | 0.91 | CA14 (0.47) | CA14HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL16522402 | 0.87 | CA14 (0.43) | CA14HDAC1HDAC2HDAC6SSTR4 | |
| SCHEMBL3487849 | 0.86 | CA14 (0.50) | CA14HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL31436149 | 0.86 | CA14 (0.42) | CA14HDAC1HDAC2HDAC6SSTR4 | |
| SCHEMBL2248633 | 0.84 | CA14 (0.46) | CA14HDAC1HDAC2HDAC6SSTR4 | |
| SCHEMBL4696802 | 0.84 | CA14 (0.46) | CA14HDAC1HDAC2HDAC6SSTR4 | |
| SCHEMBL17949691 | 0.84 | CA14 (0.43) | CA14HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL11521511 | 0.82 | CA14 (0.39) | CA14HDAC1HDAC2HDAC3NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110066224-A | Product containing lipid | 阿尔尼拉姆医药品有限公司 | 2019-07-30 | — | — | CN | disclosed |
| WO-2009013444-A1 | TETRAHYDROPYRROLOPYRIMIDINEDIONES AND THEIR USE AS HUMAN NEUTROPHIL ELASTASE INHIBITORS | ARGENTA DISCOVERY LIMITED (GB) | 2009-01-29 | — | — | WO | disclosed |