SCHEMBL3941589 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	HTT	P42858	6/20	0.57

▸	SMN1; SMN2	Q16637	4/20	0.57

▸	KMT2A	Q03164	4/20	0.57

▸	LMNA	P02545	3/20	0.57

▸	TSHR	P16473	2/20	0.57

▸	MEN1	O00255	2/20	0.57

▸	ALDH1A1	P00352	4/20	0.53

▸	PKM	P14618	4/20	0.48

▸	KDM4E	B2RXH2	1/20	0.47

▸	POLB	P06746	2/20	0.45

▸	USP2	O75604	1/20	0.45

▸	MAPT	P10636	1/20	0.45

▸	MAPK1	P28482	1/20	0.45

▸	RXFP1	Q9HBX9	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3944533	0.94	HTT (0.54)	HTTSMN1; SMN2KMT2ALMNATSHR
SCHEMBL3948692	0.93	HTT (0.63)	HTTSMN1; SMN2KMT2ALMNATSHR
SCHEMBL3945166	0.93	HTT (0.57)	HTTSMN1; SMN2KMT2ALMNATSHR
SCHEMBL3944960	0.92	HTT (0.54)	HTTSMN1; SMN2KMT2ALMNATSHR
SCHEMBL3951713	0.91	HTT (0.52)	HTTSMN1; SMN2KMT2ALMNATSHR
SCHEMBL3947900	0.90	HTT (0.63)	HTTSMN1; SMN2KMT2ALMNATSHR
SCHEMBL3951093	0.90	HTT (0.55)	HTTSMN1; SMN2KMT2ALMNATSHR
SCHEMBL3952033	0.89	HTT (0.55)	HTTSMN1; SMN2KMT2ALMNATSHR
SCHEMBL3942911	0.89	HTT (0.63)	HTTSMN1; SMN2KMT2ALMNATSHR
SCHEMBL3949273	0.89	HTT (0.67)	HTTSMN1; SMN2KMT2ALMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2009020457-A2	CHEMICAL COMPOUNDS	SMITHKLINE BEECHAM CORPORATION (US)	2009-02-12	—	—	WO	disclosed