Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
| ▸ | MELK | Q14680 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947149 | 0.90 | PTGER1 (0.41) | NPC1RAB9AMAPTF2PLG | |
| SCHEMBL13944614 | 0.83 | CD274 (0.42) | NPC1RAB9AMAPTROCK2F2 | |
| SCHEMBL13944420 | 0.82 | PTK2 (0.44) | NPC1RAB9AMAPTROCK2F2 | |
| SCHEMBL3941850 | 0.81 | NPC1 (0.44) | NPC1RAB9AMAPTROCK2F2 | |
| Hydrochloric Acid SCHEMBL3944447 | 0.80 | NPC1 (0.43) | NPC1RAB9AMAPTROCK2F2 | |
| SCHEMBL3942819 | 0.79 | SLC2A1 (0.45) | NPC1RAB9AMAPTROCK2F2 | |
| SCHEMBL13943971 | 0.79 | MELK (0.46) | NPC1RAB9AMAPTROCK2F2 | |
| SCHEMBL13943970 | 0.78 | PTGER1 (0.43) | NPC1RAB9AMAPTF2PLG | |
| SCHEMBL3946101 | 0.78 | SLC2A1 (0.41) | NPC1RAB9AMAPTROCK2F2 | |
| Hydrochloric Acid SCHEMBL3946111 | 0.78 | SLC2A1 (0.46) | NPC1RAB9AMAPTROCK2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016216-A1 | TRIAZOLE DERIVATIVES AS SCD INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-05 | — | — | WO | disclosed |