Carbamic Acid

Carbamic Acid

SCHEMBL3943348

CC(=O)Nc1nc(CCc2ccc(NC=NC(=O)O)cc2)c(CN(C)C(=O)C(F)(F)F)s1.NC(=O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 20/20 0.46
MAOB P27338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL4873619 0.91 AOC3 (0.49) AOC3MAOB
Carbamic Acid SCHEMBL4989595 0.89 AOC3 (0.51) AOC3MAOB
Carbamic Acid SCHEMBL3935872 0.86 AOC3 (0.46) AOC3MAOB
Carbamic Acid SCHEMBL3939590 0.86 AOC3 (0.46) AOC3MAOB
Carbamic Acid SCHEMBL4984607 0.83 AOC3 (0.49) AOC3MAOB
Carbamic Acid SCHEMBL4871502 0.83 AOC3 (0.46) AOC3MAOB
Carbamic Acid SCHEMBL3930911 0.83 AOC3 (0.55) AOC3
Carbamic Acid SCHEMBL5670154 0.83 AOC3 (0.52) AOC3MAOB
Carbamic Acid SCHEMBL3933648 0.83 AOC3 (0.54) AOC3MAOB
Carbamic Acid SCHEMBL5670662 0.83 AOC3 (0.49) AOC3MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1786792-B1 THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY ASTELLAS PHARMA INC (JP) 2009-04-08 EP disclosed