Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 1.00 |
| ▸ | PPARA | Q07869 | 19/20 | 1.00 |
| ▸ | PPARG | P37231 | 15/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3945228 | 0.90 | PPARD (0.82) | PPARDPPARAPPARG | |
| SCHEMBL6498633 | 0.89 | PPARA (0.86) | PPARDPPARAPPARG | |
| SCHEMBL18644833 | 0.88 | PPARA (1.00) | PPARDPPARAPPARG | |
| SCHEMBL23752211 | 0.88 | PPARA (1.00) | PPARDPPARAPPARG | |
| SCHEMBL3945781 | 0.85 | PPARA (1.00) | PPARDPPARAPPARG | |
| SCHEMBL3945192 | 0.85 | PPARA (1.00) | PPARDPPARAPPARG | |
| SCHEMBL6374864 | 0.85 | PPARA (1.00) | PPARDPPARAPPARG | |
| SCHEMBL3945771 | 0.85 | PPARA (1.00) | PPARDPPARAPPARG | |
| SCHEMBL6502352 | 0.84 | PPARA (0.79) | PPARDPPARAPPARG | |
| SCHEMBL6505382 | 0.83 | PPARA (0.81) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1285908-B9 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2009-04-22 | — | — | EP | claimed |
| EP-1285908-B1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2008-09-10 | — | — | EP | claimed |
| US-7049342-B2 | Substituted phenylpropionic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2006-05-23 | — | — | US | claimed |
| US-20030187068-A1 | Substituted phenylpropionic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-10-02 | — | — | US | claimed |
| EP-1285908-A1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-02-26 | — | — | EP | claimed |
| EP-1285908-B9 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2009-04-22 | — | — | EP | disclosed |
| EP-1285908-B1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2008-09-10 | — | — | EP | disclosed |
| US-7049342-B2 | Substituted phenylpropionic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2006-05-23 | — | — | US | disclosed |
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| US-20030187068-A1 | Substituted phenylpropionic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1285908-A1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-02-26 | — | — | EP | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187068-A1 | Substituted phenylpropionic acid derivatives | PPARA, PPARG, PPARD | PPARD 3/4885PPARA 1/4885PPARG 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.