⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8579139 | 0.92 | KDM1A (0.32) | — | |
| SCHEMBL2339926 | 0.90 | KDM1A (0.31) | — | |
| SCHEMBL6410670 | 0.79 | — | — | |
| SCHEMBL28498142 | 0.79 | — | — | |
| SCHEMBL28498133 | 0.79 | — | — | |
| SCHEMBL28984586 | 0.79 | — | — | |
| SCHEMBL28514545 | 0.74 | — | — | |
| SCHEMBL7598535 | 0.72 | — | — | |
| SCHEMBL20146186 | 0.72 | — | — | |
| SCHEMBL28507709 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667634-B2 | Inhibitors of RAF kinases | KINNATE BIOPHARMA INC. (US) | 2023-06-06 | — | — | US | disclosed |
| CN-115611703-B | Hydrofluorocycloalkanes and preparation method and application thereof | 北京宇极科技发展有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-115611703-A | Hydrofluorocycloalkane, process for its preparation and its use | 北京宇极科技发展有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-112980396-B | Ring skeleton fluorine-containing heat transfer fluid, preparation method and application thereof | 泉州宇极新材料科技有限公司 | 2022-04-12 | — | — | CN | disclosed |
| WO-2021233752-A1 | TRPA1 ANTAGONISTS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH PAIN AND INFLAMMATION | BAYER AKTIENGESELLSCHAFT (DE) | 2021-11-25 | — | — | WO | disclosed |
| CN-112980396-A | Ring skeleton fluorine-containing heat transfer fluid, preparation method and application thereof | 泉州宇极新材料科技有限公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-112094627-B | Ring skeleton fluorine-containing heat transfer fluid, preparation method and application thereof | 北京宇极科技发展有限公司 | 2021-03-16 | — | — | CN | disclosed |
| CN-112094627-A | Ring skeleton fluorine-containing heat transfer fluid, preparation method and application thereof | 北京宇极科技发展有限公司 | 2020-12-18 | — | — | CN | disclosed |
| CN-107324982-B | 1-trifluoromethyl-tetrasubstituted cyclopentene derivative and preparation method and application thereof | 华东师范大学 | 2020-07-14 | — | — | CN | disclosed |
| CN-107324982-A | Substituted cyclopentene derivative of 1 trifluoromethyl four and its preparation method and application | 华东师范大学 | 2017-11-07 | — | — | CN | disclosed |
| EP-2332953-A1 | SUBSTITUTED AMINE DERIVATIVE AND MEDICINAL COMPOSITION COMPRISING SAME AS THE ACTIVE INGREDIENT | Kotobuki Pharmaceutical Co., Ltd. (JP) | 2011-06-15 | — | — | EP | disclosed |
| WO-2009019219-A2 | METHODS OF USING A SOLVENT OR A FOAM BLOWING AGENT | Solvay (Société Anonyme) (BE) | 2009-02-12 | — | — | WO | disclosed |
| EP-0724566-A1 | 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011883-A1 | 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1995-05-04 | — | — | WO | disclosed |
| US-4293717-A | Process for preparing aldehydes and diols | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-06 | — | — | US | disclosed |
| US-3972944-A | BORON OXIDE, BORIC ACID OR BORATE AND VANADIUM OR MOLYBDENUM CONTAINING CATALYST | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-03 | — | — | US | disclosed |