Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 17/20 | 0.67 |
| ▸ | MAOB | P27338 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3939953 | 0.93 | AOC3 (0.73) | AOC3MAOBSMN1; SMN2KMT2A | |
| SCHEMBL3934030 | 0.90 | AOC3 (0.70) | AOC3MAOBSMN1; SMN2KMT2A | |
| SCHEMBL3943479 | 0.89 | AOC3 (0.68) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL3943210 | 0.87 | AOC3 (0.65) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL3932588 | 0.86 | AOC3 (0.71) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL3943351 | 0.85 | AOC3 (0.69) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL3939971 | 0.85 | AOC3 (0.73) | AOC3MAOBSMN1; SMN2KMT2A | |
| SCHEMBL3939152 | 0.85 | AOC3 (0.73) | AOC3MAOBSMN1; SMN2KMT2A | |
| SCHEMBL5550194 | 0.84 | AOC3 (0.68) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL27646789 | 0.84 | AOC3 (0.68) | AOC3MAOBSMN1; SMN2KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786792-B1 | THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY | ASTELLAS PHARMA INC (JP) | 2009-04-08 | — | — | EP | disclosed |