Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3940998 | 0.93 | CCR1 (0.72) | CCR1 | |
| SCHEMBL3940718 | 0.91 | CCR1 (0.69) | CCR1 | |
| SCHEMBL2160111 | 0.91 | CCR1 (0.80) | CCR1 | |
| SCHEMBL2160120 | 0.91 | CCR1 (0.80) | CCR1 | |
| SCHEMBL3950548 | 0.89 | CCR1 (0.82) | CCR1 | |
| SCHEMBL3007118 | 0.89 | CCR1 (1.00) | CCR1 | |
| SCHEMBL3007113 | 0.89 | CCR1 (1.00) | CCR1 | |
| SCHEMBL3943809 | 0.89 | CCR1 (1.00) | CCR1 | |
| SCHEMBL3940502 | 0.88 | CCR1 (0.73) | CCR1 | |
| SCHEMBL12400585 | 0.87 | CCR1 (0.79) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049486-A2 | PIPERIDINYL DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Company (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2007092681-A2 | PIPERIDINYL DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |