Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | ESRRB | O95718 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 7/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710903 | 1.00 | CYP2D6 (0.47) | CYP2D6CA12CA14HDAC3HDAC1 | |
| SCHEMBL3951735 | 1.00 | CYP2D6 (0.47) | CYP2D6CA12CA14HDAC3HDAC1 | |
| SCHEMBL10703266 | 0.88 | CYP2D6 (0.46) | CYP2D6CA12CA14HDAC3HDAC1 | |
| SCHEMBL12526882 | 0.88 | CYP2D6 (0.46) | CYP2D6CA12CA14HDAC3HDAC1 | |
| SCHEMBL14275181 | 0.84 | CYP2D6 (0.40) | CYP2D6CA12CA14HDAC3HDAC1 | |
| SCHEMBL2310137 | 0.84 | CYP2D6 (0.40) | CYP2D6CA12CA14HDAC3HDAC1 | |
| SCHEMBL2351134 | 0.84 | CYP2D6 (0.40) | CYP2D6CA12CA14HDAC3HDAC1 | |
| SCHEMBL1926433 | 0.82 | CYP2D6 (0.42) | CYP2D6CA12CA14HDAC3HDAC1 | |
| SCHEMBL22035318 | 0.82 | CYP2D6 (0.42) | CYP2D6CA12CA14HDAC3HDAC1 | |
| SCHEMBL2616309 | 0.81 | CA12 (0.39) | CYP2D6CA12CA14HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7512309-B2 | Polymer composition, plastic optical fiber, plastic optical fiber cable, and method for manufacturing plastic optical fiber | MITSUBISHI RAYON CO, LTD. (JP) | 2009-03-31 | — | — | US | disclosed |
| US-20080166091-A1 | Polymer Composition, Plastic Optical Fiber, Plastic Optical Fiber Cable, and Method for Manufacturing Plastic Optical Fiber | MITSUBISHI RAYON CO., LTD. (JP) | 2008-07-10 | — | — | US | disclosed |
| EP-1834968-A1 | POLYMER COMPOSITION, PLASTIC OPTICAL FIBER, PLASTIC OPTICAL FIBER CABLE AND METHOD FOR PRODUCING PLASTIC OPTICAL FIBER | Mitsubishi Rayon Co., Ltd. (JP) | 2007-09-19 | — | — | EP | disclosed |
| EP-1047690-A1 | HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 2000-11-02 | — | — | EP | disclosed |
| US-5948793-A | 3-pyridyloxymethyl heterocyclic ether compounds useful in controlling neurotransmitter release | ABBOTT LABORATORIES (US) | 1999-09-07 | — | — | US | disclosed |
| WO-1999032480-A1 | HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1999-07-01 | — | — | WO | disclosed |
| US-5914328-A | CONTROL DOPAMINE RELEASE, ACTIVATE CHOLINERGIC CHANNELS | ABBOTT LABORATORIES (US) | 1999-06-22 | — | — | US | disclosed |