Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.72 |
| ▸ | PPARG | P37231 | 10/20 | 0.63 |
| ▸ | PPARD | Q03181 | 9/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947259 | 0.92 | PPARA (0.72) | PPARAPPARGPPARDALDH1A1CYP1A2 | |
| SCHEMBL3945109 | 0.92 | PPARA (0.61) | PPARAPPARGPPARDALDH1A1CYP1A2 | |
| SCHEMBL3943656 | 0.84 | PPARA (0.62) | PPARAPPARGPPARDALDH1A1CYP1A2 | |
| SCHEMBL3943622 | 0.84 | PPARA (0.73) | PPARAPPARGPPARD | |
| SCHEMBL3942730 | 0.84 | PPARA (1.00) | PPARAPPARGPPARD | |
| SCHEMBL3942737 | 0.84 | PPARA (1.00) | PPARAPPARGPPARD | |
| SCHEMBL6495887 | 0.79 | PPARA (0.76) | PPARAPPARGPPARD | |
| SCHEMBL6505749 | 0.78 | PPARA (0.64) | PPARAPPARGPPARDALDH1A1 | |
| SCHEMBL6373752 | 0.78 | PPARA (1.00) | PPARAPPARGPPARDEPHX2 | |
| SCHEMBL6373745 | 0.78 | PPARA (1.00) | PPARAPPARGPPARDEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1285908-B9 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2009-04-22 | — | — | EP | claimed |
| EP-1285908-B1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2008-09-10 | — | — | EP | claimed |
| US-7049342-B2 | Substituted phenylpropionic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2006-05-23 | — | — | US | claimed |
| US-20030187068-A1 | Substituted phenylpropionic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-10-02 | — | — | US | claimed |
| EP-1285908-A1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-02-26 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187068-A1 | Substituted phenylpropionic acid derivatives | PPARA, PPARG, PPARD | PPARA 1/4885PPARG 2/4885PPARD 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.