Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3943534 | 0.93 | RXFP1 (0.40) | RXFP1 | |
| SCHEMBL3950755 | 0.90 | RXFP1 (0.53) | RXFP1TSHRHTTMAPK10 | |
| SCHEMBL3951299 | 0.90 | RXFP1 (0.46) | RXFP1 | |
| SCHEMBL3941702 | 0.90 | RXFP1 (0.47) | RXFP1TSHRHTTMAPK10 | |
| SCHEMBL3943104 | 0.89 | RXFP1 (0.44) | RXFP1TSHRHTTMAPK10 | |
| SCHEMBL3945458 | 0.88 | RXFP1 (0.51) | RXFP1 | |
| SCHEMBL3949121 | 0.88 | RXFP1 (0.60) | RXFP1TSHRHTTMAPK10 | |
| SCHEMBL3950417 | 0.87 | HTT (0.49) | TSHRHTT | |
| SCHEMBL3952043 | 0.87 | RXFP1 (0.47) | RXFP1TSHRHTTMAPK10 | |
| SCHEMBL3951199 | 0.86 | RXFP1 (0.48) | RXFP1TSHRHTTMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |