Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 20/20 | 0.96 |
| ▸ | CPT1B | Q92523 | 19/20 | 0.96 |
| ▸ | CPT2 | P23786 | 5/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2903517 | 0.98 | CPT1A (1.00) | CPT1ACPT1BCPT2 | |
| SCHEMBL3838202 | 0.95 | CPT1A (0.96) | CPT1ACPT1BCPT2 | |
| SCHEMBL2903667 | 0.93 | CPT1A (1.00) | CPT1ACPT1BCPT2 | |
| SCHEMBL3837062 | 0.91 | CPT1A (0.97) | CPT1ACPT1BCPT2 | |
| SCHEMBL2904429 | 0.90 | CPT1A (0.85) | CPT1ACPT1BCPT2 | |
| SCHEMBL3945257 | 0.90 | CPT1A (0.85) | CPT1ACPT1BCPT2 | |
| SCHEMBL2905345 | 0.89 | CPT1A (1.00) | CPT1ACPT1BCPT2 | |
| SCHEMBL752594 | 0.85 | CPT1A (1.00) | CPT1ACPT1BCPT2 | |
| SCHEMBL3838204 | 0.85 | CPT1A (0.84) | CPT1ACPT1BCPT2 | |
| SCHEMBL2898313 | 0.85 | CPT1A (0.84) | CPT1ACPT1BCPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097373-A1 | SULFONAMIDE DERIVATIVES AS LIVER CARNITINE PALMITOYL TRANSFERASE (L-CPTL ) | F. Hoffmann-Roche AG (CH) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008074692-A1 | SULFONAMIDE DERIVATIVES AS LIVER CARNITINE PALMITOYL TRANSFERASE (L-CPTL ) | F. HOFFMANN-LA ROCHE AG (CH) | 2008-06-26 | — | — | WO | disclosed |