SCHEMBL3946002

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10202129	0.90	EPHX2 (0.81)	EPHX2HPGDSALDH1A1TP53HPGD
	SCHEMBL3939174	0.88	EPHX2 (1.00)	EPHX2HPGDPRKAB2PRKAG1PRKAA2
	SCHEMBL3934244	0.88	EPHX2 (1.00)	EPHX2HPGDSALDH1A1TP53HPGD
	SCHEMBL3347907	0.86	EPHX2 (1.00)	EPHX2HPGDSALDH1A1TP53HPGD
	SCHEMBL15871715	0.86	EPHX2 (0.75)	EPHX2ALDH1A1TP53HPGDHTT
	SCHEMBL3936950	0.84	EPHX2 (0.72)	EPHX2HPGDSALDH1A1TP53HPGD
	SCHEMBL3946025	0.83	EPHX2 (0.71)	EPHX2HPGDSALDH1A1TP53HPGD
	SCHEMBL10268102	0.83	EPHX2 (0.71)	EPHX2ALDH1A1TP53HPGDHTT
	SCHEMBL20458861	0.83	EPHX2 (0.71)	EPHX2ALDH1A1TP53HPGDHTT
	SCHEMBL3941583	0.82	EPHX2 (1.00)	EPHX2HPGDSMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.