Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.59 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.59 |
| ▸ | SELL | P14151 | 3/20 | 0.44 |
| ▸ | SELP | P16109 | 3/20 | 0.44 |
| ▸ | SELE | P16581 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GJB2 | P29033 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sucrose SCHEMBL16859920 | 1.00 | CDK1 (0.59) | CDK1CCNB1SELLSELPSELE | |
| Sucrose SCHEMBL949885 | 1.00 | CDK1 (0.59) | CDK1CCNB1SELLSELPSELE | |
| Sucrose SCHEMBL5030245 | 1.00 | CDK1 (0.59) | CDK1CCNB1SELLSELPSELE | |
| Sucrose SCHEMBL285512 | 1.00 | CDK1 (0.59) | CDK1CCNB1SELLSELPSELE | |
| Sucrose SCHEMBL18141748 | 1.00 | CDK1 (0.59) | CDK1CCNB1SELLSELPSELE | |
| Sucrose SCHEMBL21121139 | 1.00 | CDK1 (0.59) | CDK1CCNB1SELLSELPSELE | |
| Sucrose SCHEMBL1067854 | 1.00 | CDK1 (0.59) | CDK1CCNB1SELLSELPSELE | |
| Sucrose SCHEMBL1878330 | 1.00 | CDK1 (0.59) | CDK1CCNB1SELLSELPSELE | |
| Sucrose SCHEMBL1874820 | 1.00 | CDK1 (0.59) | CDK1CCNB1SELLSELPSELE | |
| Sucrose SCHEMBL285432 | 1.00 | CDK1 (0.59) | CDK1CCNB1SELLSELPSELE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051697-A2 | FOAMABLE VEHICLE COMPRISING DICARBOXYLIC ACID OR DICARBOXYLIC ACID ESTER AND PHARMACEUTICAL COMPOSITIONS THEREOF | Foamix Ltd. (IL) | 2009-04-29 | — | — | EP | claimed |
| WO-2008038147-A2 | FOAMABLE VEHICLE COMPRISING DICARBOXYLIC ACID OR DICARBOXYLIC ACID ESTER AND PHARMACEUTICAL COMPOSITIONS THEREOF | FOAMIX LTD. (US) | 2008-04-03 | — | — | WO | claimed |
| US-20080044444-A1 | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof | FOAMIX LTD. (IL) | 2008-02-21 | — | — | US | claimed |
| US-11033491-B2 | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof | VYNE THERAPEUTICS INC. (US) | 2021-06-15 | — | — | US | disclosed |
| US-20210038517-A1 | DICARBOXYLIC ACID FOAMABLE VEHICLE AND PHARMACEUTICAL COMPOSITIONS THEREOF | VYNE THERAPEUTICS INC. (F/K/A MENLO THERAPEUTICS INC. AND SUCCESSOR-IN-INTEREST TO VYNE PHARMACEUTICALS LTD., F/K/A FOAMIX PHARMACEUTICALS LTD.) | 2021-02-11 | — | — | US | disclosed |
| US-10821077-B2 | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof | FOAMIX PHARMACEUTICALS LTD. (IL) | 2020-11-03 | — | — | US | disclosed |
| US-20200078298-A1 | Dicarboxylic Acid Foamable Vehicle and Pharmaceutical Compositions Thereof | FOAMIX PHARMACEUTICALS LTD. | 2020-03-12 | — | — | US | disclosed |
| US-20190247310-A9 | DICARBOXYLIC ACID FOAMABLE VEHICLE AND PHARMACEUTICAL COMPOSITIONS THEREOF | FOAMIX PHARMACEUTICALS LTD. (IL) | 2019-08-15 | — | — | US | disclosed |
| US-10322085-B2 | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof | FOAMIX PHARMACEUTICALS LTD. (IL) | 2019-06-18 | — | — | US | disclosed |
| US-20190076356-A1 | Dicarboxylic Acid Foamable Vehicle and Pharmaceutical Compositions Thereof | VYNE THERAPEUTICS INC. (F/K/A MENLO THERAPEUTICS INC. AND SUCCESSOR-IN-INTEREST TO VYNE PHARMACEUTICALS LTD., F/K/A FOAMIX PHARMACEUTICALS LTD.) | 2019-03-14 | — | — | US | disclosed |
| US-20190022001-A1 | DICARBOXYLIC ACID FOAMABLE VEHICLE AND PHARMACEUTICAL COMPOSITIONS THEREOF | FOAMIX PHARMACEUTICALS LTD. (IL) | 2019-01-24 | — | — | US | disclosed |
| US-9265725-B2 | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof | FOAMIX PHARMACEUTICALS LTD. (IL) | 2016-02-23 | — | — | US | disclosed |
| EP-2494959-B1 | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof | FOAMIX LTD (IL) | 2014-11-19 | — | — | EP | disclosed |
| US-20130189195-A1 | DICARBOXYLIC ACID FOAMABLE VEHICLE AND PHARMACEUTICAL COMPOSITIONS THEREOF | FOAMIX LTD. (IL) | 2013-07-25 | — | — | US | disclosed |
| EP-2494959-A1 | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof | Foamix Ltd. (IL) | 2012-09-05 | — | — | EP | disclosed |
| EP-2051697-A2 | FOAMABLE VEHICLE COMPRISING DICARBOXYLIC ACID OR DICARBOXYLIC ACID ESTER AND PHARMACEUTICAL COMPOSITIONS THEREOF | Foamix Ltd. (IL) | 2009-04-29 | — | — | EP | disclosed |
| WO-2008038147-A2 | FOAMABLE VEHICLE COMPRISING DICARBOXYLIC ACID OR DICARBOXYLIC ACID ESTER AND PHARMACEUTICAL COMPOSITIONS THEREOF | FOAMIX LTD. (US) | 2008-04-03 | — | — | WO | disclosed |
| US-20080044444-A1 | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof | FOAMIX LTD. (IL) | 2008-02-21 | — | — | US | disclosed |