Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 3/20 | 0.66 |
| ▸ | ABL1 | P00519 | 9/20 | 0.58 |
| ▸ | KIT | P10721 | 3/20 | 0.58 |
| ▸ | LDLR | P01130 | 2/20 | 0.58 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.58 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.58 |
| ▸ | BCR | P11274 | 5/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
| ▸ | KDR | P35968 | 2/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.57 |
| ▸ | BRAF | P15056 | 3/20 | 0.56 |
| ▸ | LYN | P07948 | 2/20 | 0.56 |
| ▸ | EPHB2 | P29323 | 2/20 | 0.56 |
| ▸ | TEK | Q02763 | 2/20 | 0.56 |
| ▸ | LCK | P06239 | 2/20 | 0.56 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4176681 | 0.92 | CSF1R (0.60) | CSF1RABL1KITLDLRPDGFRB | |
| SCHEMBL3952991 | 0.91 | ABL1 (0.68) | CSF1RABL1KITLDLRPDGFRB | |
| SCHEMBL3947972 | 0.91 | ABL1 (0.72) | CSF1RABL1KITLDLRPDGFRB | |
| SCHEMBL3949137 | 0.90 | CSF1R (0.56) | CSF1RABL1KITLDLRPDGFRB | |
| SCHEMBL3948664 | 0.88 | ABL1 (0.62) | CSF1RABL1KITLDLRPDGFRB | |
| SCHEMBL3945311 | 0.87 | ABL1 (0.76) | CSF1RABL1KITLDLRPDGFRB | |
| SCHEMBL3949140 | 0.86 | CSF1R (0.59) | CSF1RABL1KITLDLRPDGFRB | |
| SCHEMBL1653562 | 0.86 | ABL1 (0.76) | CSF1RABL1KITLDLRPDGFRB | |
| SCHEMBL3947962 | 0.86 | CSF1R (0.58) | CSF1RABL1KITLDLRPDGFRB | |
| SCHEMBL22548961 | 0.83 | CSF1R (0.71) | CSF1RABL1KITLDLRPCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1922309-B1 | N-PHENYL-2-PYRIMIDINE-AMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | IL YANG PHARM CO LTD (KR) | 2014-05-21 | — | — | EP | disclosed |
| US-7501424-B2 | N-phenyl-2-pyrimidine-amine derivatives and process for the preparation thereof | IL-YANG PHARM. CO., LTD. (KR) | 2009-03-10 | — | — | US | disclosed |
| US-20080096899-A1 | N-Phenyl-2-Pyrimidine-Amine Derivatives and Process for the Preparation Thereof | IL-YANG PHARM. CO., LTD. (KR) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096899-A1 | N-Phenyl-2-Pyrimidine-Amine Derivatives and Process for the Preparation Thereof | ITPA, TYMP, THPO | CSF1R 1031/4885ABL1 451/4885KIT 131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.