Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.58 |
| ▸ | CNR1 | P21554 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947516 | 1.00 | CNR2 (0.58) | CNR2CNR1ALDH1A1KDM4ENPC1 | |
| SCHEMBL3945028 | 1.00 | CNR2 (0.58) | CNR2CNR1ALDH1A1KDM4ENPC1 | |
| SCHEMBL3952718 | 0.91 | CNR2 (0.52) | CNR2CNR1ALDH1A1KDM4ENPC1 | |
| SCHEMBL3956669 | 0.91 | CNR2 (0.52) | CNR2CNR1ALDH1A1KDM4ENPC1 | |
| SCHEMBL3957589 | 0.91 | CNR2 (0.52) | CNR2CNR1ALDH1A1KDM4ENPC1 | |
| SCHEMBL5627497 | 0.88 | CNR2 (0.74) | CNR2CNR1NPC1RAB9A | |
| SCHEMBL5623950 | 0.88 | CNR2 (0.74) | CNR2CNR1NPC1RAB9A | |
| SCHEMBL3955645 | 0.85 | HTT (0.49) | CNR2CNR1ALDH1A1KDM4ERAB9A | |
| SCHEMBL3946733 | 0.85 | HTT (0.49) | CNR2CNR1ALDH1A1KDM4ERAB9A | |
| SCHEMBL3955641 | 0.85 | HTT (0.49) | CNR2CNR1ALDH1A1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544676-B2 | Sulfamoyl benzamides and methods of their use | ADOLOR CORPORATION (US) | 2009-06-09 | — | — | US | claimed |