⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31026689 | 0.98 | ANPEP (0.41) | — | |
| SCHEMBL7935092 | 0.86 | MEN1 (0.44) | — | |
| SCHEMBL19145361 | 0.84 | MEN1 (0.47) | — | |
| SCHEMBL1025215 | 0.83 | — | — | |
| SCHEMBL15925196 | 0.83 | — | — | |
| SCHEMBL26020020 | 0.83 | — | — | |
| SCHEMBL22277155 | 0.82 | MEN1 (0.50) | — | |
| SCHEMBL18601807 | 0.82 | MEN1 (0.50) | — | |
| SCHEMBL5089242 | 0.82 | MEN1 (0.50) | — | |
| SCHEMBL20067166 | 0.82 | ANPEP (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100412073-C | Novel thiophenecarboxamidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | DIMENSIONAL PHARM INC (US) | 2008-08-20 | — | — | CN | claimed |
| CN-1989120-A | Guanidine derivatives and their therapeutic use | MERCK PATENT GMBH (DE) | 2007-06-27 | — | — | CN | claimed |
| CN-1665800-A | Novel thiophenecarboxamidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | DIMENSIONAL PHARM INC (US) | 2005-09-07 | — | — | CN | claimed |
| US-12291588-B2 | Fluoropolymer compositions comprising a curing agent with ethylenically unsaturated and electron donor groups, and substrates coated therewith | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2025-05-06 | — | — | US | disclosed |
| CN-114600201-B | Electronic communication articles and methods comprising crosslinked fluoropolymers | 3M创新有限公司 | 2024-10-01 | — | — | CN | disclosed |
| EP-3807369-B1 | FLUOROPOLYMER COMPOSITIONS COMPRISING FLUORINATED ADDITIVES, COATED SUBSTRATES AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2024-07-24 | — | — | EP | disclosed |
| US-20240227357-A1 | Fluoropolymer Compositions and Methods Suitable for Copper Substrates and Electronic Telecommunications Articles | 3M INNOVATIVE PROPERTIES COMPANY | 2024-07-11 | — | — | US | disclosed |
| WO-2024123663-A1 | ANTIMICROBIAL COMPOUNDS | SRI INTERNATIONAL (US) | 2024-06-13 | — | — | WO | disclosed |
| US-20240117086-A1 | Fluoropolymer Compositions Comprising A Curing Agent with Ethylenically Unsaturated and Electron Donor Groups, and Substrates Coated Therewith | 3M INNOVATIVE PROPERTIES COMPANY | 2024-04-11 | — | — | US | disclosed |
| US-20240052191-A1 | Electronic Telecommunications Articles Comprising Crosslinked Fluoropolymer and Fluoropolymer Particles, Compositions and Methods | 3M INNOVATIVE PROPERTIES COMPANY | 2024-02-15 | — | — | US | disclosed |
| US-11866602-B2 | Fluoropolymer compositions comprising fluorinated additives, coated substrates and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2024-01-09 | — | — | US | disclosed |
| US-20070105135-A1 | Charged compounds comprising a nucleic acid binding moiety and uses therefor | GENESOFT PHARMACEUTICALS, INC. (US) | 2007-05-10 | — | — | US | disclosed |
| WO-2006088798-A2 | MODULATION OF HYPOTHALAMIC ATP-SENSITIVE POTASSIUM CHANNELS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2006-08-24 | — | — | WO | disclosed |
| CN-1665800-A | Novel thiophenecarboxamidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | DIMENSIONAL PHARM INC (US) | 2005-09-07 | — | — | CN | disclosed |
| EP-1263857-A2 | CURABLE PERFLUOROELASTOMER COMPOSITION | DUPONT DOW ELASTOMERS L.L.C. (US) | 2002-12-11 | — | — | EP | disclosed |
| US-20020026014-A1 | Curable perfluoroelastomer composition | DUPONT POLYMERS, INC. | 2002-02-28 | — | — | US | disclosed |
| WO-2001059005-A2 | CURABLE PERFLUOROELASTOMER COMPOSITION | DUPONT DOW ELASTOMERS L.L.C. (US) | 2001-08-16 | — | — | WO | disclosed |
| EP-0584088-A4 | SUBSTITUTED GUANIDINES AND DERIVATIVES THEREOF AS MODULATORS OF NEUROTRANSMITTER RELEASE AND NOVEL METHODOLOGY FOR IDENTIFYING NEUROTRANSMITTER RELEASE BLOCKERS. | CAMBRIDGE NEUROSCIENCE RES (US) | 1995-01-18 | — | — | EP | disclosed |
| EP-0584088-A1 | SUBSTITUTED GUANIDINES AND DERIVATIVES THEREOF AS MODULATORS OF NEUROTRANSMITTER RELEASE AND NOVEL METHODOLOGY FOR IDENTIFYING NEUROTRANSMITTER RELEASE BLOCKERS | CAMBRIDGE NEUROSCIENCE RESEARCH, INC. (US) | 1994-03-02 | — | — | EP | disclosed |
| WO-1992014697-A1 | SUBSTITUTED GUANIDINES AND DERIVATIVES THEREOF AS MODULATORS OF NEUROTRANSMITTER RELEASE AND NOVEL METHODOLOGY FOR IDENTIFYING NEUROTRANSMITTER RELEASE BLOCKERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1992-09-03 | — | — | WO | disclosed |