Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.59 |
| ▸ | BCHE | P06276 | 4/20 | 0.59 |
| ▸ | ACHE | P22303 | 4/20 | 0.59 |
| ▸ | WHR1 | P49842 | 1/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.55 |
| ▸ | MERTK | Q12866 | 5/20 | 0.50 |
| ▸ | ACP1 | P24666 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3949263 | 0.86 | BCHE (0.58) | APPBCHEACHEWHR1NPY5R | |
| SCHEMBL3940588 | 0.86 | BCHE (0.58) | APPBCHEACHEWHR1NPY5R | |
| SCHEMBL13793907 | 0.85 | APP (0.52) | APPBCHEACHEWHR1NPY5R | |
| SCHEMBL13793576 | 0.85 | APP (0.52) | APPBCHEACHEWHR1NPY5R | |
| SCHEMBL3939325 | 0.80 | MCHR1 (0.61) | APPBCHEACHENPY5R | |
| SCHEMBL3939323 | 0.80 | MCHR1 (0.61) | APPBCHEACHENPY5R | |
| Hydrochloric Acid SCHEMBL3943726 | 0.79 | MCHR1 (0.60) | APPBCHEACHENPY5R | |
| SCHEMBL3943751 | 0.77 | APP (0.48) | APPBCHEACHEWHR1NPY5R | |
| SCHEMBL3943754 | 0.77 | APP (0.48) | APPBCHEACHEWHR1NPY5R | |
| SCHEMBL3942516 | 0.77 | NPY5R (0.53) | APPBCHEACHEWHR1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-20070037836-A1 | Melanin concentrating hormone; obesity and related disorders, anxiety, or depression; trans-4-Bromo-N-{4-[(4-dimethylamino-quinazolin-2-ylamino)-methyl]-cyclohexylmethyl}-2-trifluoromethoxy-benzenesulfonamide | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037836-A1 | Melanin concentrating hormone; obesity and related disorders, anxiety, or depression; trans-4-Bromo-N-{4-[(4-dimethylamino-quinazolin-2-ylamino)-methyl]-cyclohexylmethyl}-2-trifluoromethoxy-benzenesulfonamide | MCHR1, MCHR2, MC4R | APP 3921/4885BCHE 2164/4885ACHE 3900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.