Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4036638 | 0.92 | HTR2A (0.64) | HTR2AHTR2C | |
| SCHEMBL3944946 | 0.91 | HTR2A (0.62) | HTR2AHTR2C | |
| SCHEMBL4036483 | 0.87 | HTR2A (0.66) | HTR2AHTR2C | |
| SCHEMBL3953998 | 0.86 | HTR2A (0.72) | HTR2AHTR2C | |
| SCHEMBL3948519 | 0.84 | HTR2A (0.72) | HTR2AHTR2C | |
| SCHEMBL4039151 | 0.83 | HTR2A (0.67) | HTR2AHTR2C | |
| SCHEMBL3949294 | 0.83 | HTR2A (0.71) | HTR2AHTR2C | |
| SCHEMBL5056285 | 0.82 | HTR2A (0.83) | HTR2AHTR2C | |
| SCHEMBL29573693 | 0.82 | HTR2A (0.83) | HTR2AHTR2C | |
| SCHEMBL3949327 | 0.82 | HTR2A (0.70) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051978-A2 | ACETAMIDE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2009-04-29 | — | — | EP | disclosed |
| WO-2007136875-A2 | ACETAMIDE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2007-11-29 | — | — | WO | disclosed |