SCHEMBL3948666

SCHEMBL3948666

SCCC1CCCc2cccnc21

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
CXCR4 P61073 14/20 0.40
CYP2D6 P10635 3/20 0.39
CYP19A1 P11511 1/20 0.37
TBXAS1 P24557 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3950796 0.86 HDAC1 (0.43) HDAC1HDAC6CXCR4CYP2D6CYP19A1
SCHEMBL27859375 0.84 HDAC1 (0.40) HDAC1HDAC6CXCR4CYP2D6CYP19A1
SCHEMBL14071365 0.84 CYP2D6 (0.42) HDAC1HDAC6CXCR4CYP2D6
SCHEMBL3952160 0.84 HDAC1 (0.40) HDAC1HDAC6CXCR4CYP2D6CYP19A1
SCHEMBL4350910 0.82 CXCR4 (0.42) CXCR4CYP2D6
SCHEMBL10367296 0.82 CXCR4 (0.51) CXCR4CYP2D6
SCHEMBL24858718 0.81 CYP2D6 (0.43) HDAC1HDAC6CXCR4CYP2D6
SCHEMBL30584967 0.81 CXCR4 (0.46) HDAC1HDAC6CXCR4CYP2D6
SCHEMBL21202393 0.81 CYP2D6 (0.43) HDAC1HDAC6CXCR4CYP2D6
SCHEMBL14037800 0.81 CXCR4 (0.46) HDAC1HDAC6CXCR4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009022279-A2 QUINOLINE AS CONTRAST AGENT IN LASER INDUCED FLUORESCENCE (LIF) FOR LESIONS KONINKLIJKE PHILIPS ELECTRONICS N. V. (NL) 2009-02-19 WO disclosed