Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | CDC25A | P30304 | 1/20 | 0.59 |
| ▸ | CDC25B | P30305 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MYC | P01106 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28658551 | 1.00 | KDM4E (0.62) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| Acetic Acid SCHEMBL28378441 | 1.00 | KDM4E (0.62) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| Acetic Acid SCHEMBL28378940 | 1.00 | KDM4E (0.62) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| Acetic Acid SCHEMBL17891250 | 0.98 | KDM4E (0.60) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| Methyl Alcohol SCHEMBL29156163 | 0.93 | KDM4E (0.64) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| SCHEMBL29899307 | 0.93 | KDM4E (0.69) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| SCHEMBL29350135 | 0.93 | KDM4E (0.69) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| SCHEMBL23861 | 0.93 | KDM4E (0.69) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| SCHEMBL23279 | 0.93 | KDM4E (0.69) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| SCHEMBL30163040 | 0.93 | KDM4E (0.69) | KDM4EHSD17B10CDC25ACDC25BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 21211 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12042535-B2 | Methods to prepare nasopharyngeal and oral material for oral inoculation of COVID-19 | HAYDEN STEVEN MARK (US) | 2024-07-23 | — | — | US | claimed |
| EP-3925601-B1 | GASTRO-RESISTANT FORMULATION CONTAINING POSACONAZOLE AND A POLYMERIC PRECIPITATION INHIBITOR | TIEFENBACHER ALFRED E GMBH & CO KG (DE) | 2024-07-17 | — | — | EP | claimed |
| US-12036324-B2 | Self-righting systems and related components and methods | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-07-16 | — | — | US | claimed |
| US-20240226103-A1 | SOLID DISPERSION OF A HER2 INHIBITOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-07-11 | — | — | US | claimed |
| CN-118284415-A | Darotamine pharmaceutical composition and preparation method and application thereof | 上海宣泰医药科技股份有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-118252869-A | Formulation comprising omega-3 fatty acid salts and gum resin extract from boswellia species | 赢创运营有限公司 | 2024-06-28 | — | — | CN | claimed |
| US-20240207264-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING INHIBITORS OF THE ANDROGEN RECEPTOR AND USES THEREOF | ESSA PHARMA INC. (CA) | 2024-06-27 | — | — | US | claimed |
| WO-2024133289-A1 | SOLID DISPERSION OF A HER2 INHIBITOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-06-27 | — | — | WO | claimed |
| US-20240197639-A1 | CAPSULE FOR SPECIFIC DRUG DELIVERY AND PREPARATION METHOD THEREFOR | JIANGSU HENGRUI PHARMACEUTICALS CO., LTD. (CN) | 2024-06-20 | — | — | US | claimed |
| CN-118215468-A | Nanocrystalline preparation of ROCK2 inhibitor and preparation method thereof | 北京泰德制药股份有限公司 | 2024-06-18 | — | — | CN | claimed |
| EP-0391518-A2 | Sustained-release pharmaceutical preparation | KINAFORM TECHNOLOGY, INC. (US) | 1990-10-10 | — | — | EP | claimed |
| US-4960814-A | FORMING PSEUDOLATICES BY CONTACTING A WATER-INSOUBLE POLYMER AND WATER-IMMISCIBLE VOLATILE SOLVENT WITH OIL IN WATER AND WATER IN OIL EMULSIFIERS | EASTMAN KODAK COMPANY (US) | 1990-10-02 | — | — | US | claimed |
| EP-0377517-A2 | Theophylline dosage form | F.H. FAULDING & CO. LIMITED (AU) | 1990-07-11 | — | — | EP | claimed |
| EP-0377477-A1 | Process for microencapsulation | BROCADES PHARMA B.V. (NL) | 1990-07-11 | — | — | EP | claimed |
| EP-0377518-A2 | Sustained release pharmaceutical composition | F.H. FAULDING & CO. LIMITED (AU) | 1990-07-11 | — | — | EP | claimed |
| US-4895725-A | Microencapsulation of fish oil | CLINICAL TECHNOLOGIES ASSOCIATES, INC. (US) | 1990-01-23 | — | — | US | claimed |
| EP-0336662-A2 | Microencapsulation of fish oil | CLINICAL TECHNOLOGIES ASSOCIATES, INC. (US) | 1989-10-11 | — | — | EP | claimed |
| EP-0327295-A2 | Tetracycline dosage form | F.H. FAULDING & CO. LTD. (AU) | 1989-08-09 | — | — | EP | claimed |
| EP-0303853-A2 | Polymer blends having reverse phase morphology for controlled delivery of bioactive agents | EASTMAN CHEMICAL COMPANY (US) | 1989-02-22 | — | — | EP | claimed |
| US-4795641-A | CELLULOSE ACETATES | EASTMAN KODAK COMPANY (US) | 1989-01-03 | — | — | US | claimed |