SCHEMBL3949022

SCHEMBL3949022

CNc1ccc(C(=O)NC2C3(C)CCC(C3)C2(C)C)cc1S(=O)(=O)N(C)CCOC

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 20/20 0.61
CNR1 P21554 16/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13793985 1.00 CNR2 (0.61) CNR2CNR1
SCHEMBL3950211 1.00 CNR2 (0.61) CNR2CNR1
SCHEMBL3946755 0.91 CNR2 (0.65) CNR2CNR1
SCHEMBL13795353 0.91 CNR2 (0.65) CNR2CNR1
SCHEMBL3949284 0.91 CNR2 (0.65) CNR2CNR1
SCHEMBL3951344 0.91 CNR2 (0.60) CNR2CNR1
SCHEMBL13794097 0.91 CNR2 (0.60) CNR2CNR1
SCHEMBL3944924 0.91 CNR2 (0.60) CNR2CNR1
SCHEMBL5626340 0.90 CNR2 (0.63) CNR2CNR1
SCHEMBL5623336 0.90 CNR2 (0.63) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7544676-B2 Sulfamoyl benzamides and methods of their use ADOLOR CORPORATION (US) 2009-06-09 US claimed
US-20080058302-A1 Sulfamoyl Benzamides and Methods of Their Use CALIXA THERAPEUTICS, INC. 2008-03-06 US claimed
US-7544676-B2 Sulfamoyl benzamides and methods of their use ADOLOR CORPORATION (US) 2009-06-09 US disclosed
US-20080058302-A1 Sulfamoyl Benzamides and Methods of Their Use CALIXA THERAPEUTICS, INC. 2008-03-06 US disclosed
WO-2007058960-A1 SULFAMOYL BENZAMIDES AS CANNABINOID RECEPTOR MODULATORS ADOLOR CORPORATION (US) 2007-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080058302-A1 Sulfamoyl Benzamides and Methods of Their Use CNR2, TRPV1, CNR1 CNR2 1/4885CNR1 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.