⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27851304 | 0.69 | JAK2 (0.39) | — | |
| SCHEMBL16445619 | 0.69 | KDM4E (0.39) | — | |
| SCHEMBL8091109 | 0.68 | — | — | |
| SCHEMBL30475376 | 0.68 | — | — | |
| SCHEMBL4240507 | 0.68 | — | — | |
| SCHEMBL482079 | 0.68 | — | — | |
| SCHEMBL2662014 | 0.68 | — | — | |
| SCHEMBL17037403 | 0.68 | — | — | |
| Iodide SCHEMBL11482211 | 0.67 | — | — | |
| SCHEMBL1894921 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080145514-A1 | Compositions and methods for coating medical implants | ANGIOTECH INTERNATIONAL AG (CH) | 2008-06-19 | — | — | US | claimed |
| US-20080113000-A1 | Compositions and methods for coating medical implants | ANGIOTECH INTERNATIONAL AG (CH) | 2008-05-15 | — | — | US | claimed |
| EP-3204043-B1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER WITH 5-IODO-2-PYRIMIDINONE-2'-DEOXYRIBOSE (IPdR) | KINSELLA TIMOTHY J (US) | 2023-06-07 | — | — | EP | disclosed |
| EP-3204043-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER WITH 5-IODO-2-PYRIMIDINONE-2'-DEOXYRIBOSE (IPdR) | Kinsella, Timothy J. (US) | 2017-08-16 | — | — | EP | disclosed |
| WO-2016057699-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER WITH 5-IODO-2-PYRIMIDINONE-2'-DEOXYRIBOSE (IPdR) | KINSELLA TIMOTHY J (US) | 2016-04-14 | — | — | WO | disclosed |
| EP-1774039-A4 | GENETIC MARKERS FOR PREDICTING DISEASE AND TREATMENT OUTCOME | UNIV SOUTHERN CALIFORNIA (US) | 2009-07-08 | — | — | EP | disclosed |
| EP-1774039-A2 | GENETIC MARKERS FOR PREDICTING DISEASE AND TREATMENT OUTCOME | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2007-04-18 | — | — | EP | disclosed |
| US-20060115827-A1 | Genetic markers for predicting disease and treatment outcome | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2006-06-01 | — | — | US | disclosed |
| WO-2006012361-A2 | GENETIC MARKERS FOR PREDICTING DISEASE AND TREATMENT OUTCOME | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2006-02-02 | — | — | WO | disclosed |