Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2J2 | P51589 | 13/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.72 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.72 |
| ▸ | HRH1 | P35367 | 4/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311000 | 0.94 | CYP2J2 (0.90) | CYP2J2CYP3A4CYP2C9CYP2B6HRH1 | |
| SCHEMBL11798280 | 0.93 | CYP2J2 (0.84) | CYP2J2CYP3A4CYP2C9CYP2B6HRH1 | |
| Hydrochloric Acid SCHEMBL11541690 | 0.92 | CYP2J2 (0.83) | CYP2J2CYP3A4CYP2C9CYP2B6HRH1 | |
| SCHEMBL11384917 | 0.91 | CYP2J2 (0.66) | CYP2J2CYP3A4CYP2C9CYP2B6HRH1 | |
| SCHEMBL11857495 | 0.90 | CYP2J2 (0.79) | CYP2J2CYP3A4CYP2C9CYP2B6HRH1 | |
| SCHEMBL17023758 | 0.89 | CYP2J2 (0.78) | CYP2J2CYP3A4CYP2C9CYP2B6HRH1 | |
| Water SCHEMBL6325014 | 0.89 | CYP2J2 (0.74) | CYP2J2CYP3A4CYP2C9CYP2B6HRH1 | |
| SCHEMBL11857642 | 0.89 | CYP2J2 (0.77) | CYP2J2CYP3A4CYP2C9CYP2B6HRH1 | |
| Hydrochloric Acid SCHEMBL11863146 | 0.89 | CYP2J2 (0.77) | CYP2J2CYP3A4CYP2C9CYP2B6HRH1 | |
| Hydrochloric Acid SCHEMBL11830971 | 0.88 | CYP2J2 (0.94) | CYP2J2CYP3A4CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034582-A2 | PROCESS FOR THE PREPARATION OF AMORPHOUS FEXOFENADINE HYDROCHLORIDE | IND-SWIFT LABORATORIES LIMITED (IN) | 2009-03-19 | — | — | WO | disclosed |
| US-20070106078-A1 | Process for the preparation of fexofenadine | RANBAXY LABORATORIES LIMITED (IN) | 2007-05-10 | — | — | US | disclosed |
| EP-1592662-A1 | PROCESS FOR THE PREPARATION OF FEXOFENADINE | Ranbaxy Laboratories Limited (IN) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004067511-A1 | PROCESS FOR THE PREPARATION OF FEXOFENADINE | RANBAXY LABORATORIES LIMITED (IN) | 2004-08-12 | — | — | WO | disclosed |
| US-4285957-A | ANTIALLERGENS; ANTIHISTAMINES; BRONCHODILATOR AGENTS | RICHARDSON-MERRELL INC. (US) | 1981-08-25 | — | — | US | disclosed |
| US-4254129-A | ANTIALLERGENS, BRONCHODILATORS, ANTIHISTAMINES; 4-DIPHENYLMETHYL PIPERIDINO-ALKANOLS | RICHARDSON-MERRELL INC. (US) | 1981-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070106078-A1 | Process for the preparation of fexofenadine | HRH2, HRH1, CYP2F1 | CYP2J2 146/4885CYP3A4 20/4885CYP2C9 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.