Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.61 |
| ▸ | MGAM | O43451 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4138620 | 0.87 | CNR2 (0.62) | CNR2MGAMSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL9867679 | 0.85 | CNR2 (0.65) | CNR2MGAMSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL7832199 | 0.76 | CNR2 (1.00) | CNR2MGAMSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL28605670 | 0.76 | CNR2 (0.62) | CNR2MGAMSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL30227109 | 0.76 | CNR2 (1.00) | CNR2MGAMSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL27838449 | 0.74 | CNR2 (0.96) | CNR2MGAMSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL7978995 | 0.74 | CNR2 (0.51) | CNR2MGAMSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL8822077 | 0.74 | CNR2 (0.51) | CNR2MGAMSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL9695920 | 0.73 | CNR2 (0.59) | CNR2MGAMSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL12256867 | 0.72 | MGAM (0.64) | CNR2MGAMSMN1; SMN2KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009024095-A1 | METHOD OF MAKING AND ADMINISTERING QUINOLINE DERIVATIVES AS ANTI-CANCER AGENTS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2009-02-26 | — | — | WO | claimed |