Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetamidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28093373 | 0.92 | FFAR3 (0.58) | — | |
| Acetic Acid SCHEMBL27410274 | 0.92 | FFAR3 (0.58) | — | |
| Acetic Acid SCHEMBL28694434 | 0.92 | FFAR3 (0.58) | — | |
| Acetic Acid SCHEMBL27642205 | 0.92 | FFAR3 (0.58) | — | |
| Acetic Acid SCHEMBL28067803 | 0.92 | FFAR3 (0.58) | — | |
| Acetamidine SCHEMBL27926517 | 0.92 | — | — | |
| Acetic Acid SCHEMBL28886845 | 0.92 | FFAR3 (0.58) | — | |
| Acetic Acid SCHEMBL28512617 | 0.92 | FFAR3 (0.58) | — | |
| Acetic Acid SCHEMBL8850911 | 0.92 | FFAR3 (0.58) | — | |
| Acetic Acid SCHEMBL350569 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119591548-A | Preparation method of 5-bromo (chloro) -2-methylpyrimidine | 台州职业技术学院 | 2025-03-11 | — | — | CN | claimed |
| CN-118488770-A | Method for preparing perovskite film and solar cell in air environment | 华北电力大学 | 2024-08-13 | — | — | CN | claimed |
| CN-111117598-B | ABX based on room temperature methodnY3-nLigand regulation method and application of perovskite nano particles | 华中科技大学 | 2021-02-09 | — | — | CN | claimed |
| CN-111117598-A | ABX based on room temperature methodnY3-nLigand regulation method and application of perovskite nano particles | 华中科技大学 | 2020-05-08 | — | — | CN | claimed |
| EP-2102172-B1 | SYNTHESIS OF 4-AMINO-PYRIMIDINES | DSM IP ASSETS BV (NL) | 2015-08-12 | — | — | EP | claimed |
| US-8198443-B2 | Synthesis of 4-amino-pyrimidines scaffolds | DSM IP ASSETS B.V. (NL) | 2012-06-12 | — | — | US | claimed |
| US-20100016591-A1 | SYNTHESIS OF 4-AMINO-PYRIMIDINES SCAFFOLDS | DSM IP ASSETS B.V. (NL) | 2010-01-21 | — | — | US | claimed |
| EP-2102172-A1 | SYNTHESIS OF 4-AMINO-PYRIMIDINES | DSM IP Assets B.V. (NL) | 2009-09-23 | — | — | EP | claimed |
| EP-1972620-A1 | Synthesis of 4-amino-pyrimidines | DSMIP Assets B.V. (NL) | 2008-09-24 | — | — | EP | claimed |
| WO-2008087021-A1 | SYNTHESIS OF 4-AMINO-PYRIMIDINES | DSM IP ASSETS B.V. (NL) | 2008-07-24 | — | — | WO | claimed |
| WO-2025242872-A1 | 1H-PYRAZOLO[4,3-D]PYRIMIDINE DERIVATIVES | Apollo AP45 Limited (GB) | 2025-11-27 | — | — | WO | disclosed |
| US-20250099494-A1 | PHOSPHONIC ACID COMPOUND AND PRODRUG THEREOF, AND PREPARATION METHODS FOR AND USES OF PHOSPHONIC ACID COMPOUND AND PRODRUG THEREOF | HAIHE BIOPHARMA CO., LTD. (CN) | 2025-03-27 | — | — | US | disclosed |
| CN-119591548-A | Preparation method of 5-bromo (chloro) -2-methylpyrimidine | 台州职业技术学院 | 2025-03-11 | — | — | CN | disclosed |
| CN-119591548-A | Preparation method of 5-bromo (chloro) -2-methylpyrimidine | 台州职业技术学院 | 2025-03-11 | — | — | CN | disclosed |
| EP-4139286-B1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AG (DE) | 2025-02-26 | — | — | EP | disclosed |
| US-4567257-A | Amidinium salts | THE UPJOHN COMPANY (US) | 1986-01-28 | — | — | US | disclosed |
| US-4525499-A | UNSATURATED POLYESTER AND VINYL RESIN DISPERSION STABILIZER | DAI NIPPON TORYO CO., LTD. (JP) | 1985-06-25 | — | — | US | disclosed |
| EP-0125777-A1 | Process and intermediates for preparation of 4-acetyl-2-substituted-imidazoles | PFIZER INC. (US) | 1984-11-21 | — | — | EP | disclosed |
| US-4482723-A | FORM 3-HALO-4,4-DIALKOXY-2-ALKANONE AND AN AMIDINE | PFIZER INC. (US) | 1984-11-13 | — | — | US | disclosed |
| US-4010289-A | METHOD OF MANUFACTURING SYNTHETIC RESIN FILM HAVING HIGH WRITABILITY AND PRINTABILITY | SHOWA DENKO KABUSHIKI KAISHA (JA) | 1977-03-01 | — | — | US | disclosed |