Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 19/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3940631 | 0.94 | CCR1 (0.70) | CCR1KCNH2 | |
| SCHEMBL3943636 | 0.89 | CCR1 (0.59) | CCR1KCNH2 | |
| SCHEMBL3939960 | 0.84 | CCR1 (0.67) | CCR1KCNH2 | |
| SCHEMBL10291735 | 0.82 | CCR1 (0.65) | CCR1KCNH2 | |
| SCHEMBL10291652 | 0.81 | CCR1 (0.91) | CCR1KCNH2 | |
| SCHEMBL2159331 | 0.81 | CCR1 (0.90) | CCR1KCNH2 | |
| SCHEMBL3942442 | 0.80 | CCR1 (0.74) | CCR1KCNH2 | |
| SCHEMBL2158825 | 0.80 | CCR1 (0.89) | CCR1KCNH2 | |
| SCHEMBL10291634 | 0.79 | CCR1 (0.60) | CCR1KCNH2 | |
| SCHEMBL2160049 | 0.78 | CCR1 (0.90) | CCR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049486-A2 | PIPERIDINYL DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Company (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2007092681-A2 | PIPERIDINYL DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |