Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL632282 | 0.89 | TAAR1 (0.74) | TAAR1 | |
| SCHEMBL631422 | 0.87 | TAAR1 (0.71) | TAAR1 | |
| SCHEMBL3952575 | 0.82 | TAAR1 (0.53) | TAAR1 | |
| SCHEMBL3950054 | 0.79 | TAAR1 (0.86) | TAAR1 | |
| SCHEMBL8216379 | 0.77 | TAAR1 (0.64) | TAAR1 | |
| SCHEMBL8213309 | 0.75 | TAAR1 (0.72) | TAAR1 | |
| SCHEMBL10228066 | 0.75 | TAAR1 (1.00) | TAAR1 | |
| SCHEMBL632589 | 0.75 | TAAR1 (0.72) | TAAR1 | |
| SCHEMBL30206459 | 0.75 | TAAR1 (0.52) | TAAR1 | |
| SCHEMBL8213386 | 0.74 | TAAR1 (0.73) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2076497-A1 | AMINOMETHYL-4-IMIDAZOLES | F. Hoffmann-Roche AG (CH) | 2009-07-08 | — | — | EP | claimed |
| WO-2008046757-A1 | AMINOMETHYL-4-IMIDAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-04-24 | — | — | WO | claimed |
| EP-2076497-A1 | AMINOMETHYL-4-IMIDAZOLES | F. Hoffmann-Roche AG (CH) | 2009-07-08 | — | — | EP | disclosed |
| WO-2008046757-A1 | AMINOMETHYL-4-IMIDAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-04-24 | — | — | WO | disclosed |