Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13736235 | 1.00 | KMT2A (0.48) | KMT2AMAPTHTTLMNAMAPK1 | |
| SCHEMBL16505318 | 0.95 | MAPT (0.50) | KMT2AMAPTHTTLMNAMAPK1 | |
| SCHEMBL16505317 | 0.95 | MAPT (0.50) | KMT2AMAPTHTTLMNAMAPK1 | |
| SCHEMBL2849150 | 0.82 | MAPT (0.58) | KMT2AMAPTLMNAMAPK1ALDH1A1 | |
| SCHEMBL9257335 | 0.82 | MAPT (0.65) | KMT2AMAPTHTTLMNAALDH1A1 | |
| SCHEMBL9425659 | 0.82 | MAPT (0.67) | KMT2AMAPTHTTLMNAMAPK1 | |
| SCHEMBL15771279 | 0.81 | CYP3A4 (0.52) | KMT2AMAPTHTTLMNAMAPK1 | |
| SCHEMBL1710516 | 0.81 | MAPT (0.65) | KMT2AMAPTHTTLMNAMAPK1 | |
| SCHEMBL4526192 | 0.80 | GRM5 (0.67) | KMT2AMAPTHTTLMNAMAPK1 | |
| SCHEMBL9261808 | 0.80 | KMT2A (0.47) | KMT2AMAPTHTTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727932-A1 | SMALL MOLECULE LIGANDS AND APTAMERS | MeiraGTx Gene Regulation Limited (GB) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024256870-A1 | SMALL MOLECULE LIGANDS AND APTAMERS | MEIRAGTX UK II LIMITED (GB) | 2024-12-19 | — | — | WO | disclosed |
| EP-2702063-A1 | BICYCLIC PYRIDAZINE COMPOUNDS AS PIM INHIBITORS | Amgen Inc. (US) | 2014-03-05 | — | — | EP | disclosed |
| WO-2012148775-A1 | BICYCLIC PYRIDAZINE COMPOUNDS AS PIM INHIBITORS | AMGEN INC. (US) | 2012-11-01 | — | — | WO | disclosed |
| EP-2078004-A1 | 2-AMINOTHIAZOLE-4-CARBOXYLIC AMIDES AS PROTEIN KINASE INHIBITORS | SCHERING CORPORATION (US) | 2009-07-15 | — | — | EP | disclosed |
| WO-2008054749-A1 | 2-AMINOTHIAZOLE-4-CARBOXYLIC AMIDES AS PROTEIN KINASE INHIBITORS | SCHERING CORPORATION (US) | 2008-05-08 | — | — | WO | disclosed |