Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.32 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.32 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.32 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.32 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.32 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.32 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.32 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.32 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.32 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1600804 | 1.00 | PDE2A (0.37) | PDE2AEPHX1POLBRAB9APTGDR2 | |
| SCHEMBL13905314 | 0.83 | PDE2A (0.41) | PDE2AEPHX1PTGDR2EPHX2HTR2A | |
| SCHEMBL1599606 | 0.78 | PDE2A (0.40) | PDE2AEPHX1PTGDR2EPHX2MEN1 | |
| SCHEMBL1601400 | 0.78 | PDE2A (0.37) | PDE2AEPHX1PTGDR2PSMB11PSMA7 | |
| SCHEMBL3949994 | 0.78 | PDE2A (0.37) | PDE2AEPHX1PTGDR2PSMB11PSMA7 | |
| SCHEMBL1601404 | 0.78 | PDE2A (0.37) | PDE2AEPHX1PTGDR2PSMB11PSMA7 | |
| SCHEMBL1600383 | 0.78 | PDE2A (0.40) | PDE2AEPHX1PTGDR2EPHX2MEN1 | |
| SCHEMBL1599494 | 0.76 | PDE2A (0.38) | PDE2AEPHX1PTGDR2PSMB11PSMA7 | |
| SCHEMBL1599496 | 0.76 | PDE2A (0.38) | PDE2AEPHX1PTGDR2PSMB11PSMA7 | |
| SCHEMBL1600907 | 0.76 | PDE2A (0.41) | PDE2AEPHX1PTGDR2PSMB11PSMA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009027785-A2 | 1, 3-OXAZOLE DERIVATIVES AS CETP INHIBITORS | PFIZER PRODUCTS INC. (US) | 2009-03-05 | — | — | WO | disclosed |