SCHEMBL3956017

SCHEMBL3956017

CO[Si](C)(C)C#Cc1ccccc1C#C[Si](C)(C)OC

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GRM5 P41594 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1639958 0.79 GRM5 (0.32) KDM4EMEN1ALDH1A1CYP1A2CYP3A4
SCHEMBL3952763 0.76 GRM5 (0.36) KDM4EMEN1ALDH1A1CYP1A2CYP3A4
SCHEMBL3949559 0.76 APP (0.35) GRM5
SCHEMBL3839029 0.75 KDM4E (0.49) KDM4EMEN1ALDH1A1CYP1A2CYP3A4
SCHEMBL3952806 0.74 GRM5 (0.40) GRM5
SCHEMBL649325 0.72 NQO1 (0.41) KDM4EMEN1ALDH1A1CYP1A2MAPT
SCHEMBL1638771 0.70 KDM4E (0.32) KDM4EMEN1ALDH1A1CYP1A2CYP3A4
SCHEMBL29636414 0.68 GRM5 (0.49) KDM4EMEN1ALDH1A1CYP1A2CYP3A4
SCHEMBL852452 0.68 GRM5 (0.49) KDM4EMEN1ALDH1A1CYP1A2CYP3A4
SCHEMBL1638803 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7556860-B2 Laminate and method of forming the same, insulating film, and semiconductor device JSR CORPORATION (JP) 2009-07-07 US disclosed
US-20060216531-A1 Laminate and method of forming the same, insulating film, and semiconductor device JSR CORPORATION (JP) 2006-09-28 US disclosed