Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.40 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 4/20 | 0.39 |
| ▸ | ACE | P12821 | 4/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.39 |
| ▸ | CPA1 | P15085 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3956382 | 1.00 | KMT2A (0.41) | KMT2ACA1CA2NPFFR1NPFFR2 | |
| SCHEMBL1259646 | 0.85 | KMT2A (0.46) | KMT2ACA1CA2GAAERAP2 | |
| SCHEMBL1259649 | 0.85 | KMT2A (0.46) | KMT2ACA1CA2GAAERAP2 | |
| SCHEMBL1259326 | 0.83 | KMT2A (0.43) | KMT2ACA1CA2GAAERAP2 | |
| SCHEMBL1259321 | 0.83 | KMT2A (0.43) | KMT2ACA1CA2GAAERAP2 | |
| SCHEMBL1259391 | 0.83 | KMT2A (0.43) | KMT2ACA1CA2GAAERAP2 | |
| SCHEMBL1259097 | 0.83 | MME (0.44) | MMEACEACE2CPA1ERAP2 | |
| SCHEMBL1259095 | 0.83 | MME (0.44) | MMEACEACE2CPA1ERAP2 | |
| SCHEMBL30317813 | 0.75 | CA1 (0.63) | KMT2ACA1CA2GAA | |
| SCHEMBL3889588 | 0.74 | KMT2A (0.41) | KMT2ACA1CA2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137133-A2 | 5-SUBSTITUTED-2-IMINO-THIAZOLIDINONE COMPOUNDS AND THEIR USE AS INHIBITORS OF BACTERIAL INFECTION | UNIVERSITY OF WASHINGTON (US) | 2009-11-12 | — | — | WO | disclosed |