Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 12/20 | 0.78 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | DRD4 | P21917 | 3/20 | 0.63 |
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12228161 | 0.90 | BCHE (0.72) | BCHEGAADRD4DRD2DRD3 | |
| SCHEMBL10997609 | 0.88 | BCHE (0.70) | BCHEGAADRD4DRD2DRD3 | |
| SCHEMBL5947718 | 0.84 | BCHE (0.72) | BCHEGAAMAPT | |
| SCHEMBL5947378 | 0.84 | BCHE (0.65) | BCHEGAADRD4DRD2DRD3 | |
| SCHEMBL21634316 | 0.84 | BCHE (0.63) | BCHEDRD4DRD2DRD3ADRA1D | |
| SCHEMBL14197926 | 0.82 | BCHE (0.67) | BCHEDRD4DRD2DRD3ADRA1D | |
| SCHEMBL3835443 | 0.82 | BCHE (0.63) | BCHEDRD4DRD2DRD3ADRA1D | |
| SCHEMBL21634272 | 0.82 | BCHE (0.67) | BCHEDRD4DRD2DRD3ADRA1D | |
| SCHEMBL30821653 | 0.82 | BCHE (0.67) | BCHEDRD4DRD2DRD3ADRA1D | |
| SCHEMBL5947204 | 0.82 | BCHE (0.59) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079525-A1 | CALCIUM RECEPTOR MODULATING AGENTS | Amgen Inc. (US) | 2009-07-22 | — | — | EP | claimed |
| WO-2008057282-A1 | CALCIUM RECEPTOR MODULATING AGENTS | AMGEN INC. (US) | 2008-05-15 | — | — | WO | claimed |