Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL76402 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL21935 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL29355915 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL17500037 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL896564 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL4394984 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL9723996 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL226551 | 0.94 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL21611886 | 0.94 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL226552 | 0.94 | CA4 (0.84) | CA4ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110698260-A | Pesticide-fertilizer composition, application of preparation thereof and application method | 四川国光农化股份有限公司 | 2020-01-17 | — | — | CN | claimed |
| US-4173453-A | Topical hair coloring formulation in the form of suspension, lotion and cream | CDC Research Inc. (US) | 1979-11-06 | — | — | US | claimed |
| WO-2022269779-A1 | METHOD FOR PRODUCING FERRITE FILM | 石原ケミカル株式会社 | 2022-12-29 | — | — | WO | disclosed |
| CN-109201048-B | Monoatomic catalyst and its preparing process | 清华大学深圳研究生院 | 2021-02-09 | — | — | CN | disclosed |
| CN-110698260-A | Pesticide-fertilizer composition, application of preparation thereof and application method | 四川国光农化股份有限公司 | 2020-01-17 | — | — | CN | disclosed |
| CN-104387143-A | Copper ammonium citrate preparation method | ZHENGZHOU RUIPU BIOLOG ENGINEERING CO LTD | 2015-03-04 | — | — | CN | disclosed |
| CN-104387143-A | Copper ammonium citrate preparation method | ZHENGZHOU RUIPU BIOLOG ENGINEERING CO LTD | 2015-03-04 | — | — | CN | disclosed |
| EP-1171389-B1 | COMPOSITION AND METHOD FOR SIMULTANEOUSLY PRECIPITATING METAL IONS FROM SEMICONDUCTOR WASTEWATER AND ENHANCING MICROFILTER OPERATION | NALCO CHEMICAL CO (US) | 2009-07-22 | — | — | EP | disclosed |
| EP-1171389-A4 | COMPOSITION AND METHOD FOR SIMULTANEOUSLY PRECIPITATING METAL IONS FROM SEMICONDUCTOR WASTEWATER AND ENHANCING MICROFILTER OPERATION | NALCO CHEMICAL CO (US) | 2003-04-09 | — | — | EP | disclosed |
| US-6403726-B1 | POLYMER WHICH SIMULTANEOUSLY PRECIPITATES METAL IONS FROM SEMICONDUCTOR WASTEWATER AND ENHANCES MICROFILTER OPERATION | NALCO CHEMICAL COMPANY | 2002-06-11 | — | — | US | disclosed |
| EP-1171389-A1 | COMPOSITION AND METHOD FOR SIMULTANEOUSLY PRECIPITATING METAL IONS FROM SEMICONDUCTOR WASTEWATER AND ENHANCING MICROFILTER OPERATION | NALCO CHEMICAL COMPANY (US) | 2002-01-16 | — | — | EP | disclosed |
| US-6258277-B1 | ADDING WATER-SOLUBLE POLYDIALLYLAMINEDITHIOCARBAMATE POLYMER TO SEMICONDUCTOR WASTEWATER CONTAINING ABRASIVE SOLIDS; PRECIPITATING SAID HEAVY METAL IONS; PASSING WASTEWATER THROUGH MICROFILTER TO REMOVE ABRASIVE SOLIDS AND PRECIPITATE | NALCO CHEMICAL COMPANY | 2001-07-10 | — | — | US | disclosed |
| WO-2000041974-A1 | COMPOSITION AND METHOD FOR SIMULTANEOUSLY PRECIPITATING METAL IONS FROM SEMICONDUCTOR WASTEWATER AND ENHANCING MICROFILTER OPERATION | NALCO CHEMICAL COMPANY (US) | 2000-07-20 | — | — | WO | disclosed |
| US-4173453-A | Topical hair coloring formulation in the form of suspension, lotion and cream | CDC Research Inc. (US) | 1979-11-06 | — | — | US | disclosed |