Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.33 |
| ▸ | F2R | P25116 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3961044 | 1.00 | METAP1 (0.44) | METAP1METAP2ALDH1A1MAPTSLC1A3 | |
| SCHEMBL3958289 | 1.00 | METAP1 (0.44) | METAP1METAP2ALDH1A1MAPTSLC1A3 | |
| SCHEMBL3966987 | 1.00 | METAP1 (0.44) | METAP1METAP2ALDH1A1MAPTSLC1A3 | |
| SCHEMBL3958667 | 1.00 | METAP1 (0.44) | METAP1METAP2ALDH1A1MAPTSLC1A3 | |
| SCHEMBL3967280 | 0.98 | METAP1 (0.41) | METAP1METAP2ALDH1A1MAPTSLC1A3 | |
| SCHEMBL3958014 | 0.98 | METAP1 (0.41) | METAP1METAP2ALDH1A1MAPTSLC1A3 | |
| SCHEMBL3958292 | 0.98 | METAP1 (0.41) | METAP1METAP2ALDH1A1MAPTSLC1A3 | |
| SCHEMBL3955384 | 0.95 | METAP1 (0.38) | METAP1METAP2ALDH1A1MAPTSLC1A3 | |
| SCHEMBL3958233 | 0.95 | METAP1 (0.38) | METAP1METAP2ALDH1A1MAPTSLC1A3 | |
| SCHEMBL3962889 | 0.95 | METAP1 (0.38) | METAP1METAP2ALDH1A1MAPTSLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492761-B1 | AMINO ACIDS WITH AFFINITY FOR THE ALPHA-2-DELTA-PROTEIN | WARNER LAMBERT CO (US) | 2009-07-22 | — | — | EP | claimed |