Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8265326 | 0.88 | F10 (0.65) | F10 | |
| SCHEMBL3950129 | 0.87 | F10 (0.62) | F10 | |
| SCHEMBL3952846 | 0.87 | F10 (0.61) | F10 | |
| SCHEMBL3952717 | 0.87 | F10 (0.62) | F10 | |
| SCHEMBL3950114 | 0.87 | F10 (0.61) | F10 | |
| SCHEMBL3950122 | 0.87 | F10 (0.62) | F10 | |
| SCHEMBL3950102 | 0.87 | F10 (0.61) | F10 | |
| SCHEMBL5428908 | 0.86 | F10 (0.60) | F10 | |
| SCHEMBL3956088 | 0.85 | F10 (0.59) | F10 | |
| SCHEMBL3951846 | 0.84 | F10 (0.58) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101094835-B | Diamide derivatives | HOFFMANN LA ROCHE | 2011-07-27 | — | — | CN | disclosed |
| US-20090270360-A1 | DICARBOXAMIDE DERIVATIVES | BOEHRINGER MARKUS | 2009-10-29 | — | — | US | disclosed |
| US-7501413-B2 | Dicarboxamide derivatives | HOFFMANN-LA ROCHE INC. (US) | 2009-03-10 | — | — | US | disclosed |
| CN-101094835-A | Novel diamide derivatives | HOFFMANN LA ROCHE (CH) | 2007-12-26 | — | — | CN | disclosed |
| US-20060106016-A1 | Dicarboxamide derivatives | HOFFMANN-LA ROCHE INC. | 2006-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106016-A1 | Dicarboxamide derivatives | F2, F12, TFPI | F10 8/4885 |
| US-20090270360-A1 | DICARBOXAMIDE DERIVATIVES | F2, F12, TFPI | F10 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.