Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 16/20 | 0.67 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7019616 | 0.86 | PPARD (0.72) | PPARDPPARA | |
| SCHEMBL7021758 | 0.85 | PPARD (0.49) | PPARDESR1ARESR2 | |
| SCHEMBL13680168 | 0.85 | PPARD (0.51) | PPARDPPARAFFAR1PPARG | |
| SCHEMBL7019114 | 0.85 | PPARD (0.77) | PPARDPPARA | |
| SCHEMBL3960058 | 0.85 | PPARD (0.67) | PPARDPPARAFFAR1PPARG | |
| SCHEMBL7016586 | 0.84 | PPARD (0.72) | PPARDPPARA | |
| SCHEMBL14355031 | 0.81 | PPARD (0.72) | PPARDPPARA | |
| SCHEMBL377558 | 0.80 | PPARD (1.00) | PPARDPPARA | |
| SCHEMBL17920520 | 0.79 | PPARD (0.56) | PPARDPPARAPPARG | |
| SCHEMBL7018887 | 0.79 | PPARD (0.81) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667964-B1 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | JANSSEN PHARMACEUTICA NV (BE) | 2009-07-22 | — | — | EP | claimed |
| US-20120122988-A1 | 4-(PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | CYMABAY THERAPEUTICS, INC. | 2012-05-17 | — | — | US | disclosed |
| EP-2100877-A1 | 4-((Phenoxyalkyl)thio)-phenoxyacetic acids and analogs | Janssen Pharmaceutica, N.V. (BE) | 2009-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122988-A1 | 4-(PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | PPARA, PPARG, PPARD | PPARD 3/4885PPARA 1/4885ESR1 1585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.