Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 11/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464688 | 0.91 | CNR2 (0.69) | CNR2LMNAMAPK14MAPTMAPK13 | |
| SCHEMBL1463681 | 0.90 | CNR2 (0.73) | CNR2LMNANTRK1NTRK2MAPK14 | |
| SCHEMBL1464659 | 0.84 | CNR2 (0.58) | CNR2LMNANTRK1NTRK2MAPK14 | |
| SCHEMBL3968558 | 0.81 | CNR2 (0.51) | CNR2LMNAMAPK14CNR1 | |
| SCHEMBL1465546 | 0.81 | CNR2 (0.78) | CNR2LMNAMAPK14MAPTMAPK13 | |
| SCHEMBL1464857 | 0.81 | CNR2 (0.82) | CNR2LMNAMAPK14MAPTMAPK13 | |
| SCHEMBL12095624 | 0.80 | CNR2 (0.70) | CNR2LMNAMAPK14MAPTMAPK13 | |
| SCHEMBL3959830 | 0.79 | CNR2 (0.47) | CNR2CNR1 | |
| SCHEMBL1464371 | 0.79 | CNR2 (0.65) | CNR2LMNAMAPK14MAPTMAPK13 | |
| SCHEMBL3964403 | 0.78 | CNR2 (0.51) | CNR2MAPK14CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |