Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 9/20 | 0.53 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | GBA2 | Q9HCG7 | 7/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100106 | 0.98 | GBA1 (0.56) | GBA1SPHK2SPHK1ALDH1A1TDP1 | |
| SCHEMBL11108673 | 0.98 | GBA1 (0.56) | GBA1SPHK2SPHK1ALDH1A1TDP1 | |
| SCHEMBL11098585 | 0.98 | GBA1 (0.56) | GBA1SPHK2SPHK1ALDH1A1TDP1 | |
| SCHEMBL11097329 | 0.95 | GBA1 (0.46) | GBA1SPHK2SPHK1GBA2 | |
| SCHEMBL2044382 | 0.95 | GBA1 (0.46) | GBA1SPHK2SPHK1GBA2 | |
| SCHEMBL2041117 | 0.88 | GBA1 (0.36) | GBA1SPHK2 | |
| SCHEMBL14992214 | 0.88 | GBA1 (0.36) | GBA1SPHK2 | |
| SCHEMBL9724515 | 0.83 | GBA1 (0.53) | GBA1SPHK2SPHK1ALDH1A1TDP1 | |
| SCHEMBL15886973 | 0.81 | GBA1 (0.46) | GBA1SPHK2SPHK1GBA2 | |
| SCHEMBL2038773 | 0.80 | MAPT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1319079-B1 | TALAROMYCES XYLANASE | BASF SE (DE) | 2012-09-19 | — | — | EP | disclosed |
| US-7514110-B1 | Talaromyces xylanases | BASF AKTIENGESELLSCHAFT (DE) | 2009-04-07 | — | — | US | disclosed |
| EP-1319079-A1 | TALAROMYCES XYLANASE | DSM N.V. (NL) | 2003-06-18 | — | — | EP | disclosed |
| WO-2002024926-A1 | TALAROMYCES XYLANASES | DSM N.V. (NL) | 2002-03-28 | — | — | WO | disclosed |
| EP-0871620-A4 | BIOCATALYTIC METHODS FOR SYNTHESIZING AND IDENTIFYING BIOLOGICALLY ACTIVE COMPOUNDS | ENZYMED INC (US) | 1999-10-27 | — | — | EP | disclosed |
| EP-0871620-A1 | BIOCATALYTIC METHODS FOR SYNTHESIZING AND IDENTIFYING BIOLOGICALLY ACTIVE COMPOUNDS | ENZYMED, Inc. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997010233-A9 | BIOCATALYTIC METHODS FOR SYNTHESIZING AND IDENTIFYING BIOLOGICALLY ACTIVE COMPOUNDS | — | 1997-05-09 | — | — | WO | disclosed |
| WO-1997010233-A1 | BIOCATALYTIC METHODS FOR SYNTHESIZING AND IDENTIFYING BIOLOGICALLY ACTIVE COMPOUNDS | ENZYMED, INC. (US) | 1997-03-20 | — | — | WO | disclosed |