Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860776 | 0.90 | PPARD (0.61) | PPARDPPARA | |
| SCHEMBL5862762 | 0.86 | PPARD (0.72) | PPARDPPARA | |
| SCHEMBL5861949 | 0.85 | PPARD (0.68) | PPARDPPARA | |
| SCHEMBL5861938 | 0.83 | PPARD (0.73) | PPARDPPARA | |
| SCHEMBL3958099 | 0.83 | PPARD (0.67) | PPARDPPARA | |
| SCHEMBL5861858 | 0.82 | PPARD (0.61) | PPARDPPARA | |
| SCHEMBL13899495 | 0.82 | PPARD (0.68) | PPARDPPARA | |
| SCHEMBL3241505 | 0.81 | PPARD (1.00) | PPARDPPARA | |
| SCHEMBL12159908 | 0.81 | PPARD (0.57) | PPARDPPARA | |
| SCHEMBL5519930 | 0.80 | PPARD (0.83) | PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176863-A1 | THIOPHENE DERIVATIVE PPAR MODULATORS | MANTLO NATHAN BRYAN | 2009-07-09 | — | — | US | claimed |
| US-20060094768-A1 | Thiophene derivative ppar modulators | ELI LILLY AND COMPANY | 2006-05-04 | — | — | US | claimed |
| EP-1583754-A1 | THIOPHENE DERIVATIVE PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-10-12 | — | — | EP | claimed |
| WO-2004063184-A1 | THIOPHENE DERIVATIVE PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-07-29 | — | — | WO | claimed |
| US-20090176863-A1 | THIOPHENE DERIVATIVE PPAR MODULATORS | MANTLO NATHAN BRYAN | 2009-07-09 | — | — | US | disclosed |
| US-20090176863-A1 | THIOPHENE DERIVATIVE PPAR MODULATORS | MANTLO NATHAN BRYAN | 2009-07-09 | — | — | US | disclosed |
| US-20090176863-A1 | THIOPHENE DERIVATIVE PPAR MODULATORS | MANTLO NATHAN BRYAN | 2009-07-09 | — | — | US | disclosed |
| US-7504433-B2 | Thiophene derivative PPAR modulators | ELI LILLY AND COMPANY (US) | 2009-03-17 | — | — | US | disclosed |
| US-7504433-B2 | Thiophene derivative PPAR modulators | ELI LILLY AND COMPANY (US) | 2009-03-17 | — | — | US | disclosed |
| US-7504433-B2 | Thiophene derivative PPAR modulators | ELI LILLY AND COMPANY (US) | 2009-03-17 | — | — | US | disclosed |
| US-20060094768-A1 | Thiophene derivative ppar modulators | ELI LILLY AND COMPANY | 2006-05-04 | — | — | US | disclosed |
| EP-1583754-A1 | THIOPHENE DERIVATIVE PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004063184-A1 | THIOPHENE DERIVATIVE PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176863-A1 | THIOPHENE DERIVATIVE PPAR MODULATORS | PPARA, PPARG, PPARD | PPARD 3/4885PPARA 1/4885 |
| US-20060094768-A1 | Thiophene derivative ppar modulators | PPARA, PPARG, PPARD | PPARD 3/4885PPARA 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.