Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15364641 | 1.00 | HCAR2 (0.54) | HCAR2NFE2L2KEAP1ATMGFPT1 | |
| SCHEMBL3957961 | 1.00 | HCAR2 (0.54) | HCAR2NFE2L2KEAP1ATMGFPT1 | |
| SCHEMBL3963683 | 0.94 | HCAR2 (0.42) | HCAR2NFE2L2KEAP1ATMMAPT | |
| SCHEMBL15019147 | 0.86 | HCAR2 (0.55) | HCAR2NFE2L2KEAP1ATMMAPT | |
| SCHEMBL15019149 | 0.86 | HCAR2 (0.55) | HCAR2NFE2L2KEAP1ATMMAPT | |
| SCHEMBL2671273 | 0.83 | GSTP1 (0.36) | HCAR2NFE2L2KEAP1ATMMAPT | |
| SCHEMBL303066 | 0.83 | GSTP1 (0.36) | HCAR2NFE2L2KEAP1ATMMAPT | |
| SCHEMBL15198319 | 0.82 | HCAR2 (0.52) | HCAR2NFE2L2KEAP1ATMGFPT1 | |
| SCHEMBL15364525 | 0.81 | HCAR2 (0.56) | HCAR2NFE2L2KEAP1ATMGFPT1 | |
| SCHEMBL15186432 | 0.81 | HCAR2 (0.56) | HCAR2NFE2L2KEAP1ATMGFPT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009033908-A2 | MOISTURE CROSS-LINKABLE POLYMERS BASED ON ALPHA-HETEROATOM SUBSTITUTED SILANES | WACKER CHEMIE AG (DE) | 2009-03-19 | — | — | WO | disclosed |