Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.53 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.53 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.53 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.53 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.53 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.53 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3956714 | 0.94 | APP (0.52) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1203140 | 0.94 | APP (0.52) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3961696 | 0.92 | APP (0.45) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1203030 | 0.92 | APP (0.58) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1202184 | 0.88 | APP (0.51) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3956715 | 0.86 | APP (0.44) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1203318 | 0.86 | APP (0.57) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1202463 | 0.86 | APP (0.59) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3657105 | 0.84 | APP (0.74) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3661970 | 0.84 | APP (0.74) | APPPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009036428-A2 | 1,3,4-TRISUBSTITUTED BENZENES | ENVIVO PHARMACEUTICALS, INC. (US) | 2009-03-19 | — | — | WO | disclosed |