⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4062543 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL28821719 | 0.98 | — | — | |
| SCHEMBL956232 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL8119809 | 0.95 | — | — | |
| SCHEMBL27482372 | 0.77 | — | — | |
| SCHEMBL4804071 | 0.77 | EGLN2 (0.30) | — | |
| SCHEMBL6527341 | 0.77 | KDM4E (0.32) | — | |
| SCHEMBL3070359 | 0.73 | NOTUM (0.33) | — | |
| SCHEMBL16964981 | 0.67 | — | — | |
| SCHEMBL2067806 | 0.67 | ADORA2A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737843-A4 | INHIBITORS OF AKT ACTIVITY | MERCK & CO INC (US) | 2009-01-28 | — | — | EP | claimed |
| EP-1737843-A1 | INHIBITORS OF AKT ACTIVITY | Merck & Co., Inc. (US) | 2007-01-03 | — | — | EP | claimed |
| WO-2005100344-A1 | INHIBITORS OF AKT ACTIVITY | MERCK & CO., INC. (US) | 2005-10-27 | — | — | WO | claimed |
| EP-4471029-A1 | METHIONINE ADENOSYLTRANSFERASE 2A INHIBITOR FOR TREATING MTAP DELETION-TYPE CANCER | Suzhou Genhouse Bio Co., Ltd. (CN) | 2024-12-04 | — | — | EP | disclosed |
| US-20240391923-A1 | METHIONINE ADENOSYLTRANSFERASE 2A INHIBITOR FOR TREATING MTAP DELETION-TYPE CANCER | SUZHOU GENHOUSE BIO CO., LTD. (CN) | 2024-11-28 | — | — | US | disclosed |
| CN-109666158-B | Hybrid dynamic polymer and application thereof | 厦门逍扬运动科技有限公司 | 2023-04-07 | — | — | CN | disclosed |
| WO-2021078227-A1 | FUSED HETEROARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2021-04-29 | — | — | WO | disclosed |
| CN-109666130-A | A kind of energy-absorbing method based on dynamic aggregation object | 翁秋梅 | 2019-04-23 | — | — | CN | disclosed |
| CN-109666158-A | A kind of hydridization dynamic aggregation object and its application | 翁秋梅 | 2019-04-23 | — | — | CN | disclosed |
| CN-104650062-B | A kind of nitrogenous heterocyclic thiazole and its production and use | 南开大学 | 2018-01-19 | — | — | CN | disclosed |
| EP-1879873-B1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK BIOPHARMACEUTICALS CO LTD (KR) | 2013-10-09 | — | — | EP | disclosed |
| CN-101578275-A | Anilinopiperazine derivatives and methods of use thereof | SCHERING CORP (US) | 2009-11-11 | — | — | CN | disclosed |
| CN-101472904-A | Diazepan derivatives modulators of chemokine receptors | HOFFMANN LA ROCHE (CH) | 2009-07-01 | — | — | CN | disclosed |
| EP-1737843-A4 | INHIBITORS OF AKT ACTIVITY | MERCK & CO INC (US) | 2009-01-28 | — | — | EP | disclosed |
| CN-101228138-A | Neurotherapeutic azole compounds | SK HOLDINGS CO LTD (KR) | 2008-07-23 | — | — | CN | disclosed |
| EP-1737843-A1 | INHIBITORS OF AKT ACTIVITY | Merck & Co., Inc. (US) | 2007-01-03 | — | — | EP | disclosed |
| EP-1716143-A1 | POLYHETEROCYCLIC COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | AstraZeneca AB (SE) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005100344-A1 | INHIBITORS OF AKT ACTIVITY | MERCK & CO., INC. (US) | 2005-10-27 | — | — | WO | disclosed |
| WO-2005080386-A1 | POLYHETEROCYCLIC COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | ASTRAZENECA AB (US) | 2005-09-01 | — | — | WO | disclosed |
| CN-1655785-A | N-acylpiperidine derivatives as melanocortin receptor ligands in the treatment of feeding disorders | PROCTER & GAMBLE (US) | 2005-08-17 | — | — | CN | disclosed |