Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.75 |
| ▸ | PPARA | Q07869 | 7/20 | 0.75 |
| ▸ | PPARG | P37231 | 2/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gw501516 SCHEMBL29356729 | 0.86 | PPARD (1.00) | PPARDPPARAPPARG | |
| Gw501516 SCHEMBL68714 | 0.86 | PPARD (1.00) | PPARDPPARAPPARG | |
| SCHEMBL5519969 | 0.85 | PPARD (0.98) | PPARDPPARAPPARG | |
| Gw501516 SCHEMBL1549692 | 0.84 | PPARD (0.83) | PPARDPPARAPPARG | |
| SCHEMBL27885765 | 0.84 | PPARD (0.73) | PPARDPPARAPPARG | |
| SCHEMBL2167562 | 0.84 | PPARD (0.66) | PPARDPPARAPPARG | |
| SCHEMBL27869357 | 0.82 | PPARD (0.73) | PPARDPPARAPPARG | |
| SCHEMBL6185567 | 0.82 | PPARD (0.77) | PPARDPPARAPPARG | |
| SCHEMBL30460470 | 0.82 | PPARD (0.77) | PPARDPPARAPPARG | |
| SCHEMBL5655404 | 0.82 | PPARD (0.70) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501811-B1 | PROCESS FOR PREPARING THIAZOLE DERIVATIVE AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME | SEOUL NAT UNIV IND FOUNDATION (KR) | 2009-07-15 | — | — | EP | disclosed |
| US-20090118516-A1 | Process for preparing ligands of ppardelta and the intermediate compounds for preparing the same | Kang, Heon Joong (KR) | 2009-05-07 | — | — | US | disclosed |
| US-20070179300-A1 | Process for preparing thiazole derivative and the intermediate compounds for preparing the same | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2007-08-02 | — | — | US | disclosed |
| US-7241901-B2 | Process for preparing thiazole derivative and the intermediate compounds for preparing the same | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2007-07-10 | — | — | US | disclosed |
| EP-1501811-A4 | PROCESS FOR PREPARING THIAZOLE DERIVATIVE AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME | KANG HEONJOONG (KR) | 2006-02-08 | — | — | EP | disclosed |
| US-20050176785-A1 | Process for preparing thiazole derivative and the intermediate compounds for preparing the same | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2005-08-11 | — | — | US | disclosed |
| EP-1501811-A1 | PROCESS FOR PREPARING THIAZOLE DERIVATIVE AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME | Kang, Heonjoong (KR) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003106442-A1 | PROCESS FOR PREPARING THIAZOLE DERIVATIVE AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME | KANG HEONJOONG (KR) | 2003-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179300-A1 | Process for preparing thiazole derivative and the intermediate compounds for preparing the same | PPARD, PPARG, PPARA | PPARD 1/4885PPARA 3/4885PPARG 2/4885 |
| US-20090118516-A1 | Process for preparing ligands of ppardelta and the intermediate compounds for preparing the same | PPARG, PPARD, PPARA | PPARD 2/4885PPARA 3/4885PPARG 1/4885 |
| US-20050176785-A1 | Process for preparing thiazole derivative and the intermediate compounds for preparing the same | PPARD, PPARG, PPARA | PPARD 1/4885PPARA 3/4885PPARG 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.