Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.62 |
| ▸ | CNR1 | P21554 | 10/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3961143 | 0.91 | GAA (0.50) | CNR2CNR1GAARORCABCC9 | |
| SCHEMBL4066158 | 0.86 | CNR2 (0.49) | CNR2CNR1L3MBTL1CYP2C8CYP2D6 | |
| SCHEMBL1465215 | 0.84 | CNR2 (0.46) | CNR2CNR1RORCABCC9ABCC8 | |
| SCHEMBL1466231 | 0.83 | CNR2 (0.53) | CNR2CNR1GAAABCC9ABCC8 | |
| SCHEMBL1464890 | 0.83 | CNR2 (0.70) | CNR2CNR1GAA | |
| SCHEMBL3962726 | 0.81 | CNR2 (0.53) | CNR2CNR1GAARORCABCC9 | |
| SCHEMBL1463633 | 0.80 | CNR2 (0.76) | CNR2CNR1GAA | |
| SCHEMBL3967859 | 0.79 | CNR2 (0.62) | CNR2CNR1ABCC9ABCC8KCNJ11 | |
| SCHEMBL1463732 | 0.78 | CNR2 (1.00) | CNR2CNR1GAACYP2C8CYP2D6 | |
| SCHEMBL1463528 | 0.77 | CNR2 (0.78) | CNR2CNR1GAACYP2C8CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |