Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.51 |
| ▸ | CNR1 | P21554 | 6/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3966620 | 0.99 | CNR2 (0.52) | CNR2CNR1KDM1AMAPTKDM4E | |
| SCHEMBL3964901 | 0.93 | CNR2 (0.52) | CNR2CNR1KDM1AMAPTKDM4E | |
| SCHEMBL3963536 | 0.91 | CNR2 (0.44) | CNR2CNR1KDM1AMAPTKDM4E | |
| SCHEMBL1463827 | 0.78 | CNR2 (0.51) | CNR2CNR1KDM1AMAPTKDM4E | |
| SCHEMBL1463528 | 0.77 | CNR2 (0.78) | CNR2CNR1MAPTNPSR1ALDH1A1 | |
| SCHEMBL3963505 | 0.77 | CNR2 (0.51) | CNR2CNR1MAPTALDH1A1LMNA | |
| SCHEMBL3961281 | 0.76 | CNR2 (0.59) | CNR2CNR1MAPTKDM4ENPSR1 | |
| SCHEMBL3959616 | 0.75 | CNR2 (0.41) | CNR2CNR1KDM1A | |
| SCHEMBL3964793 | 0.75 | CNR2 (0.48) | CNR2CNR1MAPTKDM4ENPSR1 | |
| SCHEMBL3959680 | 0.74 | CNR2 (0.38) | CNR2CNR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |